AIMC Topic: Aging

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Brain age of rhesus macaques over the lifespan.

Neurobiology of aging
Through the application of machine learning algorithms to neuroimaging data the brain age methodology was shown to provide a useful individual-level biological age prediction and identify key brain regions responsible for the prediction. In this stud...

Organ-specific biological clocks: Ageotyping for personalized anti-aging medicine.

Ageing research reviews
Aging is a complex multidimensional, progressive remodeling process affecting multiple organ systems. While many studies have focused on studying aging across multiple organs, assessment of the contribution of individual organs to overall aging proce...

Development, validation, and transportability of several machine-learned, non-exercise-based VO prediction models for older adults.

Journal of sport and health science
BACKGROUND: There exist few maximal oxygen uptake (VO) non-exercise-based prediction equations, fewer using machine learning (ML), and none specifically for older adults. Since direct measurement of VO is infeasible in large epidemiologic cohort stud...

Predicting the impact of CPAP on brain health: A study using the sleep EEG-derived brain age index.

Annals of clinical and translational neurology
OBJECTIVE: This longitudinal study investigated potential positive impact of CPAP treatment on brain health in individuals with obstructive sleep Apnea (OSA). To allow this, we aimed to employ sleep electroencephalogram (EEG)-derived brain age index ...

Prescription eyeglasses as a forensic physical evidence: Prediction of age based on refractive error measures using machine learning algorithm.

Journal of forensic sciences
Refractive errors (RE) are commonly reported visual impairment problems worldwide. Previous clinical studies demonstrated age-related changes in human eyes. We hypothesized that the binocular RE metrics including sphere and cylinder power, axis orien...

Deep learning models reveal replicable, generalizable, and behaviorally relevant sex differences in human functional brain organization.

Proceedings of the National Academy of Sciences of the United States of America
Sex plays a crucial role in human brain development, aging, and the manifestation of psychiatric and neurological disorders. However, our understanding of sex differences in human functional brain organization and their behavioral consequences has be...

Ranking and filtering of neuropathology features in the machine learning evaluation of dementia studies.

Brain pathology (Zurich, Switzerland)
Early diagnosis of dementia diseases, such as Alzheimer's disease, is difficult because of the time and resources needed to perform neuropsychological and pathological assessments. Given the increasing use of machine learning methods to evaluate neur...

Artificial intelligence in retinal imaging: current status and future prospects.

Expert review of medical devices
INTRODUCTION: The steadily growing and aging world population, in conjunction with continuously increasing prevalences of vision-threatening retinal diseases, is placing an increasing burden on the global healthcare system. The main challenges within...

Elderly and visually impaired indoor activity monitoring based on Wi-Fi and Deep Hybrid convolutional neural network.

Scientific reports
A drop in physical activity and a deterioration in the capacity to undertake daily life activities are both connected with ageing and have negative effects on physical and mental health. An Elderly and Visually Impaired Human Activity Monitoring (EV-...

A machine learning approach for quantifying age-related histological changes in the mouse kidney.

GeroScience
The ability to quantify aging-related changes in histological samples is important, as it allows for evaluation of interventions intended to effect health span. We used a machine learning architecture that can be trained to detect and quantify these ...