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Biological Clocks

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Unsupervised Learning in an Ensemble of Spiking Neural Networks Mediated by ITDP.

PLoS computational biology
We propose a biologically plausible architecture for unsupervised ensemble learning in a population of spiking neural network classifiers. A mixture of experts type organisation is shown to be effective, with the individual classifier outputs combine...

Biological modelling of a computational spiking neural network with neuronal avalanches.

Philosophical transactions. Series A, Mathematical, physical, and engineering sciences
In recent years, an increasing number of studies have demonstrated that networks in the brain can self-organize into a critical state where dynamics exhibit a mixture of ordered and disordered patterns. This critical branching phenomenon is termed ne...

Abnormal Low-Frequency Oscillations Reflect Trait-Like Pain Ratings in Chronic Pain Patients Revealed through a Machine Learning Approach.

The Journal of neuroscience : the official journal of the Society for Neuroscience
Measures of moment-to-moment fluctuations in brain activity of an individual at rest have been shown to be a sensitive and reliable metric for studying pathological brain mechanisms across various chronic pain patient populations. However, the relati...

Membrane potential resonance in non-oscillatory neurons interacts with synaptic connectivity to produce network oscillations.

Journal of computational neuroscience
Several neuron types have been shown to exhibit (subthreshold) membrane potential resonance (MPR), defined as the occurrence of a peak in their voltage amplitude response to oscillatory input currents at a preferred (resonant) frequency. MPR has been...

Neural network model of an amphibian ventilatory central pattern generator.

Journal of computational neuroscience
The neuronal multiunit model presented here is a formal model of the central pattern generator (CPG) of the amphibian ventilatory neural network, inspired by experimental data from Pelophylax ridibundus. The kernel of the CPG consists of three pacema...

Programmable coupled oscillators for synchronized locomotion.

Nature communications
The striking similarity between biological locomotion gaits and the evolution of phase patterns in coupled oscillatory network can be traced to the role of central pattern generator located in the spinal cord. Bio-inspired robotics aim at harnessing ...

Organ-specific biological clocks: Ageotyping for personalized anti-aging medicine.

Ageing research reviews
Aging is a complex multidimensional, progressive remodeling process affecting multiple organ systems. While many studies have focused on studying aging across multiple organs, assessment of the contribution of individual organs to overall aging proce...

A miRNA-based epigenetic molecular clock for biological skin-age prediction.

Archives of dermatological research
Skin aging is one of the visible characteristics of the aging process in humans. In recent years, different biological clocks have been generated based on protein or epigenetic markers, but few have focused on biological age in the skin. Arrest the a...

CPG-based neural control of peristaltic planar locomotion in an earthworm-like robot: evaluation of nonlinear oscillators.

Bioinspiration & biomimetics
Earthworm-like robots have excellent locomotion capability in confined environments. Central pattern generator (CPG) based controllers utilize the dynamics of coupled nonlinear oscillators to spontaneously generate actuation signals for all segments,...