MOTIVATION: Searching for precise terms and terminological definitions in the biomedical data space is problematic, as researchers find overlapping, closely related and even equivalent concepts in a single or multiple ontologies. Search engines that ...
Recent advances in biomedical research have generated a large volume of drug-related data. To effectively handle this flood of data, many initiatives have been taken to help researchers make good use of them. As the results of these initiatives, many...
With the avalanche of biological sequences generated in the post-genomic age, one of the most challenging problems is how to computationally analyze their structures and functions. Machine learning techniques are playing key roles in this field. Typi...
With the recent developments in the field of multi-omics integration, the interest in factors such as data preprocessing, choice of the integration method and the number of different omics considered had increased. In this work, the impact of these f...
MOTIVATION: Sequence-based protein-protein interaction (PPI) prediction represents a fundamental computational biology problem. To address this problem, extensive research efforts have been made to extract predefined features from the sequences. Base...
MOTIVATION: Historically, gene expression has been shown to be the most informative data for drug response prediction. Recent evidence suggests that integrating additional omics can improve the prediction accuracy which raises the question of how to ...
MOTIVATION: Alternative splicing generates multiple isoforms from a single gene, greatly increasing the functional diversity of a genome. Although gene functions have been well studied, little is known about the specific functions of isoforms, making...
Mathematical biosciences and engineering : MBE
Jul 12, 2019
Pediatricians and pediatric endocrinologists utilize Bone Age Assessment (BAA) for in-vestigations pertaining to genetic disorders, hormonal complications and abnormalities in the skeletal system maturity of children. Conventional methods dating back...
Mathematical biosciences and engineering : MBE
Jul 4, 2019
RNA modification plays an indispensable role in the regulation of organisms. RNA modification site prediction offers an insight into diverse cellular processing. Regarding different types of RNA modification site prediction, it is difficult to tell t...
Studies in health technology and informatics
Jul 4, 2019
Clinical decision support systems are data analysis software that supports health professionals' decision - making the process to reach their ultimate outcome, taking into account patient information. However, the need for decision support systems ca...
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