BACKGROUND: The complex pathogenesis of Alzheimer's disease (AD) has resulted in limited current biomarkers for its classification and diagnosis, necessitating further investigation into reliable universal biomarkers or combinations.
Alzheimer's disease (AD) constitutes a neurodegenerative disorder predominantly observed in the geriatric population. If AD can be diagnosed early, both in terms of prevention and treatment, it is very beneficial to patients. Therefore, our team prop...
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that significantly impacts cognitive function, posing a major global health challenge. Despite its rising prevalence, particularly in low and middle-income countries, early diagnosi...
Traditional diagnostic methods for Alzheimer's disease often suffer from low accuracy and lengthy processing times, delaying crucial interventions and patient care. Deep convolutional neural networks trained on MRI data can enhance diagnostic precisi...
Early diagnosis of Neurological Disorders (ND) such as Alzheimer's disease (AD) and Brain Tumors (BT) can be highly challenging since these diseases cause minor changes in the brain's anatomy. Magnetic Resonance Imaging (MRI) is a vital tool for diag...
We propose a compositional graph-based Machine Learning (ML) framework for Alzheimer's disease (AD) detection that constructs complex ML predictors from modular components. In our directed computational graph, datasets are represented as nodes [Formu...
Deep learning is significantly advancing the analysis of electroencephalography (EEG) data by effectively discovering highly nonlinear patterns within the signals. Data partitioning and cross-validation are crucial for assessing model performance and...
BMC medical informatics and decision making
Jul 1, 2025
Alzheimer's Disease (AD) poses a significant global health challenge, necessitating early and accurate diagnosis to enable timely interventions. AD is a progressive neurodegenerative disorder that affects millions worldwide and is one of the leading ...
Extracellular vesicles (EVs) in plasma are composed of exosomes, microvesicles, and apoptotic bodies. We report a plasma EV enrichment strategy using magnetic beads called Mag-Net. Proteomic interrogation of this plasma EV fraction enables the detect...
Tumor suppressor genes (TSGs) are critical regulators of cellular homeostasis and are extensively studied in cancer biology. However, their roles in neurodegenerative diseases, particularly Alzheimer's disease (AD), remain poorly understood. Recent e...
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