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Alzheimer Disease

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Hybrid-RViT: Hybridizing ResNet-50 and Vision Transformer for Enhanced Alzheimer's disease detection.

PloS one
Alzheimer's disease (AD) is a leading cause of disability worldwide. Early detection is critical for preventing progression and formulating effective treatment plans. This study aims to develop a novel deep learning (DL) model, Hybrid-RViT, to enhanc...

Alzheimer's Disease: Exploring Pathophysiological Hypotheses and the Role of Machine Learning in Drug Discovery.

International journal of molecular sciences
Alzheimer's disease (AD) is a major neurodegenerative dementia, with its complex pathophysiology challenging current treatments. Recent advancements have shifted the focus from the traditionally dominant amyloid hypothesis toward a multifactorial und...

Alzheimer's disease classification using hybrid loss Psi-Net segmentation and a new hybrid network model.

Computational biology and chemistry
Alzheimer's disease (AD) is a type of brain disorder that is becoming more prevalent worldwide. It is a progressive and irreversible condition that gradually impairs memory and cognitive abilities, eventually making it difficult to perform even basic...

A quantitatively interpretable model for Alzheimer's disease prediction using deep counterfactuals.

NeuroImage
Deep learning (DL) for predicting Alzheimer's disease (AD) has provided timely intervention in disease progression yet still demands attentive interpretability to explain how their DL models make definitive decisions. Counterfactual reasoning has rec...

Reducing inference cost of Alzheimer's disease identification using an uncertainty-aware ensemble of uni-modal and multi-modal learners.

Scientific reports
While multi-modal deep learning approaches trained using magnetic resonance imaging (MRI) and fluorodeoxyglucose positron emission tomography (FDG PET) data have shown promise in the accurate identification of Alzheimer's disease, their clinical appl...

Interpretable AI for inference of causal molecular relationships from omics data.

Science advances
The discovery of molecular relationships from high-dimensional data is a major open problem in bioinformatics. Machine learning and feature attribution models have shown great promise in this context but lack causal interpretation. Here, we show that...

Prediction of cognitive conversion within the Alzheimer's disease continuum using deep learning.

Alzheimer's research & therapy
BACKGROUND: Early diagnosis and accurate prognosis of cognitive decline in Alzheimer's disease (AD) is important to timely assignment to optimal treatment modes. We aimed to develop a deep learning model to predict cognitive conversion to guide re-as...

EEGConvNeXt: A novel convolutional neural network model for automated detection of Alzheimer's Disease and Frontotemporal Dementia using EEG signals.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Deep learning models have gained widespread adoption in healthcare for accurate diagnosis through the analysis of brain signals. Neurodegenerative disorders like Alzheimer's Disease (AD) and Frontotemporal Dementia (FD) are ...

Alzheimer's Disease detection and classification using optimized neural network.

Computers in biology and medicine
Alzheimer's disease (AD) is a degenerative neurological condition characterized by a progressive decline in cognitive abilities, resulting in memory impairment and limitations in performing daily tasks. Timely and precise identification of AD holds p...

Analyzing patterns of frequent mental distress in Alzheimer's patients: A generative AI approach.

Journal of the National Medical Association
This study tackles creating Python code for beginners with generative AI and analyzing trends in mental distress among Alzheimer's patients in the US (2015-2022 CDC data). It guides beginners through using AI to generate code for visualizing these tr...