AIMC Topic: Animals

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Deep learning-based discovery of compounds for blood pressure lowering effects.

Scientific reports
The hypotensive side effects caused by drugs during their use have been a vexing issue. Recent studies have found that deep learning can effectively predict the biological activity of compounds by mining patterns and rules in the data, providing a po...

ChromatinHD connects single-cell DNA accessibility and conformation to gene expression through scale-adaptive machine learning.

Nature communications
Gene regulation is inherently multiscale, but scale-adaptive machine learning methods that fully exploit this property in single-nucleus accessibility data are still lacking. Here, we develop ChromatinHD, a pair of scale-adaptive models that uses the...

Functional antimicrobial peptide-loaded 3D scaffolds for infected bone defect treatment with AI and multidimensional printing.

Materials horizons
Infection is the most prevalent complication of fractures, particularly in open fractures, and often leads to severe consequences. The emergence of bacterial resistance has significantly exacerbated the burden of infection in clinical practice, makin...

Unsupervised Domain Adaptation for EM Image Denoising With Invertible Networks.

IEEE transactions on medical imaging
Electron microscopy (EM) image denoising is critical for visualization and subsequent analysis. Despite the remarkable achievements of deep learning-based non-blind denoising methods, their performance drops significantly when domain shifts exist bet...

Neural networks through the lens of evolutionary dynamics.

Bio Systems
This article revisits Artificial Neural Networks (NNs) through the lens of Evolutionary Dynamics. The two most important features of NNs are shown to reflect the two most general processes of Evolutionary Dynamics. This overlap may serve as a new and...

Deep learning-enabled filter-free fluorescence microscope.

Science advances
Optical filtering is an indispensable part of fluorescence microscopy for selectively highlighting molecules labeled with a specific fluorophore and suppressing background noise. However, the utilization of optical filtering sets increases the comple...

Microbial perspective of multidisciplinary collaborative weight management approach: may serve as a key target for weight loss.

Gut microbes
Changes in the gut microbiota are associated with obesity and may influence weight loss. We are currently implementing a sustained multidisciplinary collaborative weight management (MCWM) approach to weight loss. We report significant improvements in...

Efficient and stable extraction of nano-sized plastic particles enabled by bio-inspired magnetic "robots" in water.

Environmental pollution (Barking, Essex : 1987)
In this research, a rationally-designed strategy was employed to address the crucial issue of removing nano-plastics (NPs) from aquatic environments, which was based on fabricating sea urchin-like structures of FeO magnetic robots (MagRobots). Throug...

A computational deep learning investigation of animacy perception in the human brain.

Communications biology
The functional organization of the human object vision pathway distinguishes between animate and inanimate objects. To understand animacy perception, we explore the case of zoomorphic objects resembling animals. While the perception of these objects ...

Biologically plausible gated recurrent neural networks for working memory and learning-to-learn.

PloS one
The acquisition of knowledge and skills does not occur in isolation but learning experiences amalgamate within and across domains. The process through which learning can accelerate over time is referred to as learning-to-learn or meta-learning. While...