AIMC Topic: Animals

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Automated acute skin toxicity scoring in a mouse model through deep learning.

Radiation and environmental biophysics
This study presents a novel approach to skin toxicity assessment in preclinical radiotherapy trials through an advanced imaging setup and deep learning. Skin reactions, commonly associated with undesirable side effects in radiotherapy, were meticulou...

Predictive method for poultry carcass visceral dimensions using 3D point cloud and Genetic Algorithm-based wavelet neural network.

Poultry science
In order to avoid damaging viscera during poultry evisceration and enhance the economic value of poultry products, this paper proposes a predictive method for poultry carcass visceral dimensions based on 3D point cloud and a Genetic Algorithm-based W...

Unleashing the future: The revolutionary role of machine learning and artificial intelligence in drug discovery.

European journal of pharmacology
Drug discovery is a complex and multifaceted process aimed at identifying new therapeutic compounds with the potential to treat various diseases. Traditional methods of drug discovery are often time-consuming, expensive, and characterized by low succ...

DeepCt: Predicting Pharmacokinetic Concentration-Time Curves and Compartmental Models from Chemical Structure Using Deep Learning.

Molecular pharmaceutics
After initial triaging using in vitro absorption, distribution, metabolism, and excretion (ADME) assays, pharmacokinetic (PK) studies are the first application of promising drug candidates in living mammals. Preclinical PK studies characterize the ev...

A lightweight deep-learning model for parasite egg detection in microscopy images.

Parasites & vectors
BACKGROUND: Intestinal parasitic infections are still a serious public health problem in developing countries, and the diagnosis of parasitic infections requires the first step of parasite/egg detection of samples. Automated detection can eliminate t...

A hybrid method for discovering interferon-gamma inducing peptides in human and mouse.

Scientific reports
Interferon-gamma (IFN-γ) is a versatile pleiotropic cytokine essential for both innate and adaptive immune responses. It exhibits both pro-inflammatory and anti-inflammatory properties, making it a promising therapeutic candidate for treating various...

AI-driven precision subcellular navigation with fluorescent probes.

Journal of materials chemistry. B
Precise navigation within intricate biological systems is pivotal for comprehending cellular functions and diagnosing diseases. Fluorescent molecular probes, designed to target specific biological molecules, are indispensable tools for this endeavor....

G-Protein Signaling in Alzheimer's Disease: Spatial Expression Validation of Semi-supervised Deep Learning-Based Computational Framework.

The Journal of neuroscience : the official journal of the Society for Neuroscience
Systemic study of pathogenic pathways and interrelationships underlying genes associated with Alzheimer's disease (AD) facilitates the identification of new targets for effective treatments. Recently available large-scale multiomics datasets provide ...

Estrogen-mediated modulation of sterile inflammatory markers and baroreflex sensitivity in ovariectomized female Wistar rats.

Archives of endocrinology and metabolism
OBJECTIVE: This study aims to explore the role of estrogen in providing cardioprotective benefits to premenopausal women, examining how hormonal differences between sexes influence the prevalence of cardiovascular diseases (CVDs) in women.

Monitoring poultry social dynamics using colored tags: Avian visual perception, behavioral effects, and artificial intelligence precision.

Poultry science
Artificial intelligence (AI) in animal behavior and welfare research is on the rise. AI can detect behaviors and localize animals in video recordings, thus it is a valuable tool for studying social dynamics. However, maintaining the identity of indiv...