AIMC Topic: Animals

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The effect of taxonomic, host-dependent features and sample bias on virus host prediction using machine learning and short sequence k-mers.

Scientific reports
Metaviromic studies of potential emerging infection reservoirs led to discovery of many novel viruses. Since metaviromes contain viruses from target host, its food or other sources, fast and robust approaches are needed to predict hosts of unknown vi...

A detailed guide to melt electro-writing for tissue engineering applications.

Biofabrication
Melt electro-writing (MEW) is an advanced 3D printing technique with significant potential in tissue engineering due to its ability to create highly precise microscale structures using biocompatible materials. This review provides a comprehensive gui...

Early embryo development: the current perspective in molecular evaluation and clinical status.

Systems biology in reproductive medicine
Early embryo development and competence mechanisms are paramount to ART's success but are still underexplored in human-relevant animal models. Clinical embryo evaluation remains largely based on subjectively evaluated morphological characteristics. I...

Pathogen virulence genes: Advances, challenges and future directions in infectious disease research (Review).

International journal of molecular medicine
Pathogens, including bacteria, viruses and fungi, employ virulence genes to invade their hosts, circumvent immunity and induce diseases. The present review examines the categorization and regulatory mechanisms of virulence genes and their co‑evolutio...

Classification of first embryonic division stages of multiple Caenorhabditis species by deep learning.

NPJ systems biology and applications
The first embryonic division of Caenorhabditis elegans is a model for asymmetric cell division, and identifying the stages of cell division across related species could improve our understanding of the divergence of cellular events and mechanisms. Co...

AI-enhanced rapid diagnostic testing platform for mass opisthorchiasis screening.

Scientific reports
Cholangiocarcinoma (CCA) is a prevalent malignancy in countries along Mekong basin, closely linked to chronic infections caused by Opisthorchis viverrini (OV). Early detection of OV-infected individuals holds significant promise for screening at-risk...

Intestinal bacteria translocation promotes β-cell dysfunction in DIO mice.

Scientific reports
Awareness of the intestinal microflora involved in insulin resistance and type 2 diabetes (T2DM) has now become more evident. However, direct mechanical insight is required to illustrate the contribution of intestinal microflora in the disease progre...

Machine learning framework for investigating nano- and micro-scale particle diffusion in colonic mucus.

Journal of nanobiotechnology
Biosimilar artificial mucus models that mimic native mucus facilitate efficient, lab-based drug diffusion studies, addressing the costly and challenging preclinical phase of drug development, especially for nano- and micro-scale particle-based coloni...

Flu-CNN: identifying host specificity of Influenza A virus using convolutional networks.

Human genomics
Influenza A viruses (IAVs) have historically posed significant public health threats, causing severe pandemics. Viral host specificity is typically constrained by host barriers, limiting the range of species that can be infected. However, these barri...

Biomimetic magnetobacterial microrobots for active pneumonia therapy.

Nature communications
Immense progress in synthetic micro-/nanorobots with diverse functionalities has been made for biomedical applications during the last decade. However, there is still a huge gap for miniature robots to realize efficient therapy from in vitro to in vi...