AIMC Topic: Animals

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Searching molecular structure databases with tandem mass spectra using CSI:FingerID.

Proceedings of the National Academy of Sciences of the United States of America
Metabolites provide a direct functional signature of cellular state. Untargeted metabolomics experiments usually rely on tandem MS to identify the thousands of compounds in a biological sample. Today, the vast majority of metabolites remain unknown. ...

SORTA: a system for ontology-based re-coding and technical annotation of biomedical phenotype data.

Database : the journal of biological databases and curation
There is an urgent need to standardize the semantics of biomedical data values, such as phenotypes, to enable comparative and integrative analyses. However, it is unlikely that all studies will use the same data collection protocols. As a result, ret...

Genetic Learning Particle Swarm Optimization.

IEEE transactions on cybernetics
Social learning in particle swarm optimization (PSO) helps collective efficiency, whereas individual reproduction in genetic algorithm (GA) facilitates global effectiveness. This observation recently leads to hybridizing PSO with GA for performance e...

Capnodynamic assessment of effective lung volume during cardiac output manipulations in a porcine model.

Journal of clinical monitoring and computing
A capnodynamic calculation of effective pulmonary blood flow includes a lung volume factor (ELV) that has to be estimated to solve the mathematical equation. In previous studies ELV correlated to reference methods for functional residual capacity (FR...

Sparse Markov chain-based semi-supervised multi-instance multi-label method for protein function prediction.

Journal of bioinformatics and computational biology
Automated assignment of protein function has received considerable attention in recent years for genome-wide study. With the rapid accumulation of genome sequencing data produced by high-throughput experimental techniques, the process of manually pre...

Connecting proteins with drug-like compounds: Open source drug discovery workflows with BindingDB and KNIME.

Database : the journal of biological databases and curation
Today's large, public databases of protein-small molecule interaction data are creating important new opportunities for data mining and integration. At the same time, new graphical user interface-based workflow tools offer facile alternatives to cust...

Putative synaptic genes defined from a Drosophila whole body developmental transcriptome by a machine learning approach.

BMC genomics
BACKGROUND: Assembly and function of neuronal synapses require the coordinated expression of a yet undetermined set of genes. Although roughly a thousand genes are expected to be important for this function in Drosophila melanogaster, just a few hund...

An FDES-Based Shared Control Method for Asynchronous Brain-Actuated Robot.

IEEE transactions on cybernetics
The asynchronous brain-computer interface (BCI) offers more natural human-machine interaction. However, it is still considered insufficient to control rapid and complex sequences of movements for a robot without any advanced control method. This pape...

Automated measurement of mouse social behaviors using depth sensing, video tracking, and machine learning.

Proceedings of the National Academy of Sciences of the United States of America
A lack of automated, quantitative, and accurate assessment of social behaviors in mammalian animal models has limited progress toward understanding mechanisms underlying social interactions and their disorders such as autism. Here we present a new in...

3D printing antagonistic systems of artificial muscle using projection stereolithography.

Bioinspiration & biomimetics
The detailed mechanical design of a digital mask projection stereolithgraphy system is described for the 3D printing of soft actuators. A commercially available, photopolymerizable elastomeric material is identified and characterized in its liquid an...