AIMC Topic: Animals

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2D-3D radiograph to cone-beam computed tomography (CBCT) registration for C-arm image-guided robotic surgery.

International journal of computer assisted radiology and surgery
PURPOSE: C-arm radiographs are commonly used for intraoperative image guidance in surgical interventions. Fluoroscopy is a cost-effective real-time modality, although image quality can vary greatly depending on the target anatomy. Cone-beam computed ...

Estimation of the chemical-induced eye injury using a Weight-of-Evidence (WoE) battery of 21 artificial neural network (ANN) c-QSAR models (QSAR-21): part II: corrosion potential.

Regulatory toxicology and pharmacology : RTP
This is part II of an in silico investigation of chemical-induced eye injury that was conducted at FDA's CFSAN. Serious eye damage caused by chemical (eye corrosion) is assessed using the rabbit Draize test, and this endpoint is an essential part of ...

Identifying predictive features in drug response using machine learning: opportunities and challenges.

Annual review of pharmacology and toxicology
This article reviews several techniques from machine learning that can be used to study the problem of identifying a small number of features, from among tens of thousands of measured features, that can accurately predict a drug response. Prediction ...

Active-learning strategies in computer-assisted drug discovery.

Drug discovery today
High-throughput compound screening is time and resource consuming, and considerable effort is invested into screening compound libraries, profiling, and selecting the most promising candidates for further testing. Active-learning methods assist the s...

Estimation of the chemical-induced eye injury using a weight-of-evidence (WoE) battery of 21 artificial neural network (ANN) c-QSAR models (QSAR-21): part I: irritation potential.

Regulatory toxicology and pharmacology : RTP
Evaluation of potential chemical-induced eye injury through irritation and corrosion is required to ensure occupational and consumer safety for industrial, household and cosmetic ingredient chemicals. The historical method for evaluating eye irritant...

Learning structured models for segmentation of 2-D and 3-D imagery.

IEEE transactions on medical imaging
Efficient and accurate segmentation of cellular structures in microscopic data is an essential task in medical imaging. Many state-of-the-art approaches to image segmentation use structured models whose parameters must be carefully chosen for optimal...

A computational model of the short-cut rule for 2D shape decomposition.

IEEE transactions on image processing : a publication of the IEEE Signal Processing Society
We propose a new 2D shape decomposition method based on the short-cut rule. The short-cut rule originates from cognition research, and states that the human visual system prefers to partition an object into parts using the shortest possible cuts. We ...

Robotic systems for percutaneous needle-guided interventions.

Minimally invasive therapy & allied technologies : MITAT : official journal of the Society for Minimally Invasive Therapy
Several groups have developed robotic systems for invasive medical procedures. In this article we will focus on selected robotic systems for percutaneous needle-guided interventions using CT or MR imaging. We present six interventional robotic system...

Prediction of water quality index in constructed wetlands using support vector machine.

Environmental science and pollution research international
Poor water quality is a serious problem in the world which threatens human health, ecosystems, and plant/animal life. Prediction of surface water quality is a main concern in water resource and environmental systems. In this research, the support vec...

Odorant recognition using biological responses recorded in olfactory bulb of rats.

Computers in biology and medicine
In this study we applied pattern recognition (PR) techniques to extract odorant information from local field potential (LFP) signals recorded in the olfactory bulb (OB) of rats subjected to different odorant stimuli. We claim that LFP signals registe...