AIMC Topic: Animals

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Exploiting Metabolic Defects in Glioma with Nanoparticle-Encapsulated NAMPT Inhibitors.

Molecular cancer therapeutics
The treatment of primary central nervous system tumors is challenging due to the blood-brain barrier and complex mutational profiles, which is associated with low survival rates. However, recent studies have identified common mutations in gliomas [is...

[Application of Photoplethysmography Combined with Deep Learning in Postoperative Monitoring of Flaps].

Zhongguo yi liao qi xie za zhi = Chinese journal of medical instrumentation
OBJECTIVE: Photoelectric volumetric tracing (PPG) exhibits high sensitivity and specificity in flap monitoring. Deep learning (DL) is capable of automatically and robustly extracting features from raw data. In this study, we propose combining PPG wit...

INTREPPPID-an orthologue-informed quintuplet network for cross-species prediction of protein-protein interaction.

Briefings in bioinformatics
An overwhelming majority of protein-protein interaction (PPI) studies are conducted in a select few model organisms largely due to constraints in time and cost of the associated 'wet lab' experiments. In silico PPI inference methods are ideal tools t...

Aerial Wildlife Image Repository for animal monitoring with drones in the age of artificial intelligence.

Database : the journal of biological databases and curation
Drones (unoccupied aircraft systems) have become effective tools for wildlife monitoring and conservation. Automated animal detection and classification using artificial intelligence (AI) can substantially reduce logistical and financial costs and im...

The developmental and evolutionary characteristics of transcription factor binding site clustered regions based on an explainable machine learning model.

Nucleic acids research
Gene expression is temporally and spatially regulated by the interaction of transcription factors (TFs) and cis-regulatory elements (CREs). The uneven distribution of TF binding sites across the genome poses challenges in understanding how this distr...

From data to discovery: AI-guided analysis of disease-relevant molecules in spinal muscular atrophy (SMA).

Human molecular genetics
Spinal Muscular Atrophy is caused by partial loss of survival of motoneuron (SMN) protein expression. The numerous interaction partners and mechanisms influenced by SMN loss result in a complex disease. Current treatments restore SMN protein levels t...

Internal world models in humans, animals, and AI.

Neuron
How do brains-biological or artificial-respond and adapt to an ever-changing environment? In a recent meeting, experts from various fields of neuroscience and artificial intelligence met to discuss internal world models in brains and machines, arguin...

Machine learning to identify endometrial biomarkers predictive of pregnancy success following artificial insemination in dairy cows†.

Biology of reproduction
The objective was to identify a set of genes whose transcript abundance is predictive of a cow's ability to become pregnant following artificial insemination. Endometrial epithelial cells from the uterine body were collected for RNA sequencing using ...

Geobiology: Machine learning puts bioturbation on the map.

Current biology : CB
Bioturbation, the mixing of sediment through the actions of organisms, is a crucial ecosystem engineering process that controls biogeochemical cycles and helps structure marine ecosystems. Machine learning is helping to develop global maps of the int...