AIMC Topic: Antifibrinolytic Agents

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Comparative Effectiveness of Machine Learning Approaches for Predicting Gastrointestinal Bleeds in Patients Receiving Antithrombotic Treatment.

JAMA network open May 3, 2021
IMPORTANCE: Anticipating the risk of gastrointestinal bleeding (GIB) when initiating antithrombotic treatment (oral antiplatelets or anticoagulants) is limited by existing risk prediction models. Machine learning algorithms may result in superior pre...
Humans Machine Learning Predictive Value of Tests Fibrinolytic Agents Anticoagulants Adolescent Cohort Studies United States Gastrointestinal Hemorrhage Myocardial Ischemia Thienopyridines Atrial Fibrillation Venous Thromboembolism Antifibrinolytic Agents Young Adult Female Adult Aged Cross-Sectional Studies Aged, 80 and over Male Retrospective Studies Middle Aged Clinical Decision-Making Risk Assessment
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Hip Fracture Surgery without Transfusion in Patients with Hemoglobin Less Than 10 g/dL.

Clinics in orthopedic surgery Dec 8, 2020
BACKGROUD: Hip fracture surgery is associated with blood loss, which may lead to adverse patient outcomes. The hemoglobin level declines gradually in most hip fracture cases involving femoral neck fractures and intertrochanteric fractures. It decreas...
Antifibrinolytic Agents Male Female Humans Hip Fractures Hemoglobins Trace Elements Aged Retrospective Studies Erythropoietin Iron Aged, 80 and over Tranexamic Acid
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Safety of a High-Dose Tranexamic Acid Protocol in Complex Adult Spinal Deformity: Analysis of 100 Consecutive Cases.

Spine deformity Nov 2, 2017
STUDY DESIGN: Retrospective review of high-dose tranexamic acid (TXA) use in consecutive patients.
Osteotomy Safety Tranexamic Acid Antifibrinolytic Agents Administration, Intravenous Operative Time Spinal Fusion Spine Blood Loss, Surgical Blood Transfusion Aged Adult Male Middle Aged Treatment Outcome Operative Blood Salvage Humans Retrospective Studies Female
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A systematic review and meta-analysis of the effect of prophylactic tranexamic acid treatment in major benign uterine surgery.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics Dec 9, 2016
BACKGROUND: The value of tranexamic acid (TA) treatment as bleeding prophylaxis in major uterine surgery is unclear.
Cesarean Section Blood Loss, Surgical Blood Transfusion Pregnancy Female Gynecologic Surgical Procedures Randomized Controlled Trials as Topic Tranexamic Acid Antifibrinolytic Agents Humans
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Antifibrinolytic Therapy in Surgery for Adolescent Idiopathic Scoliosis Does the Level 1 Evidence Translate to Practice?

Bulletin of the Hospital for Joint Disease (2013) Sep 1, 2018
INTRODUCTION: Previous randomized controlled trials have demonstrated the efficacy of antifibrinolytic agents in the reduction of intraoperative blood loss in adolescent idiopathic scoliosis (AIS) surgery. Tranexamic acid (TXA) was found to be more e...
Aminocaproic Acid Humans Scoliosis Female Antifibrinolytic Agents Male Practice Patterns, Physicians' Blood Loss, Surgical Adolescent Registries Cohort Studies Tranexamic Acid Child
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[Effect on time of temporarily-closed wound drainage on blood loss of primary total knee arthroplasty after intravenous and intra-articular injection of tranexamic acid].

Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery Apr 15, 2017
OBJECTIVE: To investigate the effect and safety of time of temporarily-closed wound drainage on blood loss of primary total knee arthroplasty (TKA) after intravenous and intra-articular injection of tranexamic acid (TXA).
Female Blood Loss, Surgical Blood Transfusion Drainage Postoperative Hemorrhage Tranexamic Acid Humans Arthroplasty, Replacement, Knee Antifibrinolytic Agents Injections, Intra-Articular
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