AIMC Topic: Antineoplastic Agents

Clear Filters Showing 291 to 300 of 491 articles

Artificial intelligence in nanomedicine.

Nanoscale horizons
The field of nanomedicine has made substantial strides in the areas of therapeutic and diagnostic development. For example, nanoparticle-modified drug compounds and imaging agents have resulted in markedly enhanced treatment outcomes and contrast eff...

CGPS: A machine learning-based approach integrating multiple gene set analysis tools for better prioritization of biologically relevant pathways.

Journal of genetics and genomics = Yi chuan xue bao
Gene set enrichment (GSE) analyses play an important role in the interpretation of large-scale transcriptome datasets. Multiple GSE tools can be integrated into a single method as obtaining optimal results is challenging due to the plethora of GSE to...

A robotic system to prepare IV solutions.

International journal of medical informatics
Drugs need to be used regularly and correctly in order to be effective. When medicines are used correctly, negativities that threaten human health and life can be avoided, but they can cause unwanted situations that can occur until the end of life wh...

RASPELD to Perform High-End Screening in an Academic Environment toward the Development of Cancer Therapeutics.

ChemMedChem
The identification of compounds for dissecting biological functions and the development of novel drug molecules are central tasks that often require screening campaigns. However, the required architecture is cost- and time-intensive. Herein we descri...

Drug response prediction by ensemble learning and drug-induced gene expression signatures.

Genomics
Chemotherapeutic response of cancer cells to a given compound is one of the most fundamental information one requires to design anti-cancer drugs. Recently, considerable amount of drug-induced gene expression data has become publicly available, in ad...

Machine Learning Helps Identify New Drug Mechanisms in Triple-Negative Breast Cancer.

IEEE transactions on nanobioscience
This paper demonstrates the ability of mach- ine learning approaches to identify a few genes among the 23,398 genes of the human genome to experiment on in the laboratory to establish new drug mechanisms. As a case study, this paper uses MDA-MB-231 b...

Drug Selection via Joint Push and Learning to Rank.

IEEE/ACM transactions on computational biology and bioinformatics
Selecting the right drugs for the right patients is a primary goal of precision medicine. In this article, we consider the problem of cancer drug selection in a learning-to-rank framework. We have formulated the cancer drug selection problem as to ac...

Cancer Drug Response Profile scan (CDRscan): A Deep Learning Model That Predicts Drug Effectiveness from Cancer Genomic Signature.

Scientific reports
In the era of precision medicine, cancer therapy can be tailored to an individual patient based on the genomic profile of a tumour. Despite the ever-increasing abundance of cancer genomic data, linking mutation profiles to drug efficacy remains a cha...

Deep Learning for Drug Discovery and Cancer Research: Automated Analysis of Vascularization Images.

IEEE/ACM transactions on computational biology and bioinformatics
Likely drug candidates which are identified in traditional pre-clinical drug screens often fail in patient trials, increasing the societal burden of drug discovery. A major contributing factor to this phenomenon is the failure of traditional in vitro...