INTRODUCTION: Pleiotropy describes the genetic effect of a single gene on multiple phenotypic traits. Gene variants directly affect the normal processes of a series of physiological and biochemical reactions, and therefore cause a variety of diseases...
Journal of the American Medical Informatics Association : JAMIA
Apr 29, 2015
OBJECTIVE: Analysis of narrative (text) data from electronic health records (EHRs) can improve population-scale phenotyping for clinical and genetic research. Currently, selection of text features for phenotyping algorithms is slow and laborious, req...
Rheumatoid arthritis (RA) is a systemic inflammatory autoimmune disorder that has serious physical and mental health implications. It is evident that disruptions to mitochondrial function have a considerable impact on the survival, activation, and di...
Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
Dec 15, 2025
OBJECTIVE: To explore, identify, and develop novel blood-based indicators using machine learning algorithms for accurate preoperative assessment and effective prediction of postoperative complication risks in patients with rheumatoid arthritis (RA) u...
BACKGROUND: Although studies have shown that patients with rheumatoid arthritis (RA) are at a higher risk of developing myasthenia gravis (MG), the causal relationship and shared genetic basis between these two diseases have not been fully investigat...
International journal of medical informatics
Aug 1, 2025
BACKGROUND: In light of global population aging and the increasing prevalence of Rheumatoid Arthritis (RA) with age, strategies are needed to address this public health challenge. Machine learning (ML) may play a vital role in early identification of...
OBJECTIVES: Artificial intelligence (AI) possesses considerable promise in healthcare to offer decision help in particular domains, including rheumatoid arthritis (RA). This study assesses the adherence of the advanced AI model ChatGPT-v4 to the Euro...
BACKGROUND: To develop a predictive model for bone destruction in patients with rheumatoid arthritis (RA), based on the characteristics of plasma metabolites and common clinical indicators.
OBJECTIVES: Convolutional neural networks (CNNs) are increasingly used to classify medical images, but few studies utilize smartphone photographs. The objective of this study was to assess CNNs for differentiating patients from controls and detecting...
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology
Apr 1, 2025
Objective Based on 25 indicators including immune factors, cell count classification, and smear results of the knee joint fluid, machine learning models were established to distinguish between osteoarthritis (OA) and rheumatoid arthritis (RA). Method...
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