OBJECTIVES: The objective of this study is to devise a modelling strategy for attaining in-silico models replicating human physiology and, in particular, the activity of the autonomic nervous system.
KEY POINTS: Nausea is an adverse experience characterised by alterations in autonomic and cerebral function. Susceptibility to nausea is difficult to predict, but machine learning has yet to be applied to this field of study. The severity of nausea t...
BACKGROUND: Doctors mainly use scale tests and subjective judgment in the clinical diagnosis of depression. Researches have demonstrated that depression is associated with the dysfunction of the autonomic nervous system (ANS), where its modulation ca...
Automatic sleep stage classification with cardiorespiratory signals has attracted increasing attention. In contrast to the traditional manual scoring based on polysomnography, these signals can be measured using advanced unobtrusive techniques that a...
The primary goal of surgical intervention for rectal cancer is to achieve an oncologic cure while preserving function. Since the introduction of total mesorectal excision (TME), the oncologic outcome has improved greatly in terms of local recurrence ...
Mathematical biosciences and engineering : MBE
Aug 2, 2024
Heart rate variability (HRV) is an important metric in cardiovascular health monitoring. Spectral analysis of HRV provides essential insights into the functioning of the cardiac autonomic nervous system. However, data artefacts could degrade signal q...
Drug-induced convulsions are a major challenge to drug development because of the lack of reliable biomarkers. Using machine learning, our previous research indicated the potential use of an index derived from heart rate variability (HRV) analysis in...
Studies in health technology and informatics
Jun 29, 2023
Intermittent fasting has been practiced for centuries across many cultures globally. Recently many studies have reported intermittent fasting for its lifestyle benefits, the major shift in eating habits and patterns is associated with several changes...
In both biological and engineered systems, functioning at peak power output for prolonged periods of time requires thermoregulation. Here, we report a soft hydrogel-based actuator that can maintain stable body temperatures via autonomic perspiration....
Although self-report pain ratings are the gold standard in clinical pain assessment, they are inherently subjective in nature and significantly influenced by multidimensional contextual variables. Although objective biomarkers for pain could substant...
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