AIMC Topic: Bacteria

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Meta-analysis of shotgun sequencing of gut microbiota in obese children with MASLD or MASH.

Gut microbes
Alterations in the gut microbiome affect the development and severity of metabolic dysfunction-associated steatotic liver disease (MASLD) or metabolic dysfunction-associated steatohepatitis (MASH). We analyzed microbiomes of obese children with and w...

Microbial vitamin biosynthesis links gut microbiota dynamics to chemotherapy toxicity.

mBio
Dose-limiting toxicities pose a major barrier to cancer treatment. While preclinical studies show that the gut microbiota influences and is influenced by anticancer drugs, data from patients paired with careful side effect monitoring remains limited....

Brassica microgreens shape gut microbiota and functional metabolite profiles in a species-related manner: A multi-omics approach following in vitro gastrointestinal digestion and large intestine fermentation.

Microbiological research
Brassicaceae microgreens constitute a novel and promising source of bioactive compounds, such as polyphenols and glucosinolates. In this work, an integrative computational approach was performed to decipher the interaction between bioaccessible micro...

Distinguishing critical microbial community shifts from normal temporal variability in human and environmental ecosystems.

Scientific reports
Differentiating significant microbial community changes from normal fluctuations is vital for understanding microbial dynamics in human and environmental ecosystems. This knowledge could enable early warning systems to monitor critical changes affect...

Fluorescence-based spectrometric and imaging methods and machine learning analyses for microbiota analysis.

Mikrochimica acta
Most microbiota determination (skin, gut, soil, etc.) are currently conducted in a laboratory using expensive equipment and lengthy procedures, including culture-dependent methods, nucleic acid amplifications (including quantitative PCR), DNA microar...

A novel method for achieving ecological indicator based on vertical soil bacterial communities coupled with machine learning: A case study of a typical tropical site in China.

Journal of hazardous materials
Global industrialization has resulted in severe contamination of soil with heavy metals (HMs). Nevertheless, it is unclear if it affects the depth-resolved bacterial communities. Herein, we collected soil samples at different depths from a typical HM...

Standardizing a microbiome pipeline for body fluid identification from complex crime scene stains.

Applied and environmental microbiology
Recent advances in next-generation sequencing have opened up new possibilities for applying the human microbiome in various fields, including forensics. Researchers have capitalized on the site-specific microbial communities found in different parts ...

Exploring species taxonomic kingdom using information entropy and nucleotide compositional features of coding sequences based on machine learning methods.

Methods (San Diego, Calif.)
The flow of genetic information from DNA to protein is governed by the central dogma of molecular biology. Genetic drift and mutations usually lead to changes in DNA composition, thereby affecting the coding sequences (CDS) that encode functional pro...

Deep learning-enhanced hyperspectral imaging for rapid screening of Co-metabolic microplastic-degrading bacteria in environmental samples.

Journal of hazardous materials
Microbial biodegradation of microplastic (MP) emerges as an environmentally benign and highly promising strategy for alleviating MP pollution in the ecosystem. Conventional approaches for screening MP-degrading bacteria use pollutants as the sole car...

Performance and hypothetical clinical impact of an mNGS-based machine learning model for antimicrobial susceptibility prediction of five ESKAPEE bacteria.

Microbiology spectrum
UNLABELLED: Antimicrobial resistance is an escalating global health crisis, underscoring the urgent need for timely and targeted therapies to ensure effective clinical treatment. We developed a machine learning model based on metagenomic next-generat...