AIMC Topic: Bacterial Infections

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PaPrBaG: A machine learning approach for the detection of novel pathogens from NGS data.

Scientific reports
The reliable detection of novel bacterial pathogens from next-generation sequencing data is a key challenge for microbial diagnostics. Current computational tools usually rely on sequence similarity and often fail to detect novel species when closely...

THE BIOLOGICAL ACTIVITIES OF L.

African journal of traditional, complementary, and alternative medicines : AJTCAM
BACKGROUND: Mastitis reduces milk yield and alters milk composition. Antibiotics are widely used in the treatment of the disease. However, this widespread use of antibiotics causes both antibiotic residues in milks and antibiotic resistance developed...

Fit-for-purpose chromatographic method for the determination of amikacin in human plasma for the dosage control of patients.

Talanta
In this paper, a simple, rapid and sensitive method based on liquid chromatography with fluorimetric detection (HPLC-FLD) for the determination of amikacin (AMK) in human plasma is developed. Determination is performed by pre-column derivatization of...

Combining expert knowledge and knowledge automatically acquired from electronic data sources for continued ontology evaluation and improvement.

Journal of biomedical informatics
INTRODUCTION: A common bottleneck during ontology evaluation is knowledge acquisition from domain experts for gold standard creation. This paper contributes a novel semi-automated method for evaluating the concept coverage and accuracy of biomedical ...

Phage and enzyme therapies in wound infections: From lab to bedside.

Chinese medical journal
Antibiotic-resistant (AR) bacterial wound infections (WIs) impose major burdens on healthcare systems, exacerbated by ineffective therapies and stalled antibiotic development. Phage therapy and phage-derived enzymes have gained traction as potent alt...

Identification of bacterial infection types in decomposition stages at various temperatures using pathology images and artificial intelligence algorithms.

Journal of microbiological methods
Bacterial infections present a significant threat to human health, and accurate identification of infection type is crucial for both clinical and forensic applications. Although traditional diagnostic methods are reliable, they are often time-consumi...

A solution to the postantibiotic era: phages as precision medicine.

Current opinion in microbiology
Antibiotic-resistant bacterial infections pose a significant global health challenge. Phage therapy provides a promising alternative to antibiotics that enables the specific targeting of pathogenic bacteria while preserving the healthy microbiome. Re...

Artificial intelligence in bacterial diagnostics and antimicrobial susceptibility testing: Current advances and future prospects.

Biosensors & bioelectronics
Recently, artificial intelligence (AI) has emerged as a transformative tool, enhancing the speed, accuracy, and scalability of bacterial diagnostics. This review explores the role of AI in revolutionizing bacterial detection and antimicrobial suscept...

Augmentation of Infrared Microscopy of White Blood Cells and Medical Measures for Rapid and Accurate Diagnosis of Bacterial or Viral Infections in Febrile Pediatric Oncology Patients: An Expert System-Based Study.

Analytical chemistry
Infectious diseases, a major contributor to high mortality rates, often exhibit similar symptoms, despite variations in immune responses to bacterial or viral infections. Rapidly differentiating bacterial infections from viral infections in febrile p...