Translational research of many disease areas requires a longitudinal understanding of disease development and progression across all biologically relevant scales. Several corresponding studies are now available. However, to compile a comprehensive pi...
Neural networks : the official journal of the International Neural Network Society
Jun 16, 2020
Similar to real snakes in nature, the flexible trunks of snake-like robots enhance their movement capabilities and adaptabilities in diverse environments. However, this flexibility corresponds to a complex control task involving highly redundant degr...
Diagnostic microbiology and infectious disease
Jun 8, 2020
Previous studies have shown promising results of machine learning (ML) models for predicting health outcomes. We develop and test ML models for predicting Clostridioides difficile infection (CDI) in hospitalized patients. This is a retrospective coho...
Drug-induced liver injury (DILI) is one the most unpredictable adverse reactions to xenobiotics in humans and the leading cause of postmarketing withdrawals of approved drugs. To date, these drugs have been collated by the FDA to form the DILIRank da...
PURPOSE: Accurately forecasting the occurrence of future covid-19-related cases across relaxed (Sweden) and stringent (USA and Canada) policy contexts has a renewed sense of urgency. Moreover, there is a need for a multidimensional county-level appro...
PURPOSE: While neural networks gain popularity in medical research, attempts to make the decisions of a model explainable are often only made towards the end of the development process once a high predictive accuracy has been achieved.
European journal of clinical pharmacology
Jun 1, 2020
PURPOSE: A Bayesian confidence propagation neural network (BCPNN) is a signal detection method used by the World Health Organization Uppsala Monitoring Centre to analyze spontaneous reporting system databases. We modify the BCPNN to increase its sens...
Modeling factors influencing disease phenotypes, from biomarker profiling study datasets, is a critical task in biomedicine. Such datasets are typically generated from high-throughput 'omic' technologies, which help examine disease mechanisms at an u...
MOTIVATION: Brain or central nervous system cancer is the tenth leading cause of death in men and women. Even though brain tumour is not considered as the primary cause of mortality worldwide, 40% of other types of cancer (such as lung or breast canc...
Optimizing athlete's performance is one of the most important and challenging aspects of coaching. Physiological and positional data, often acquired using wearable devices, have been useful to identify patterns, thus leading to a better understanding...
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