AIMC Topic: Biological Products

Clear Filters Showing 81 to 90 of 110 articles

Small Molecule Accurate Recognition Technology (SMART) to Enhance Natural Products Research.

Scientific reports Oct 27, 2017
Various algorithms comparing 2D NMR spectra have been explored for their ability to dereplicate natural products as well as determine molecular structures. However, spectroscopic artefacts, solvent effects, and the interactive effect of functional gr...
Cyanobacteria Biological Products Magnetic Resonance Spectroscopy Peptide Synthases Neural Networks, Computer Data Analysis
View on PubMed DOI

The Economic Burden of ACPA-Positive Status Among Patients with Rheumatoid Arthritis.

Journal of managed care & specialty pharmacy Jul 17, 2017
BACKGROUND: Anticitrullinated protein antibodies (ACPAs) are serological biomarkers associated with early, rapidly progressing rheumatoid arthritis (RA), including more severe disease and joint damage. ACPA testing has become a routine tool for RA di...
Cost of Illness Biological Products Adult Health Expenditures Antirheumatic Agents Electronic Health Records Male Middle Aged Disease Progression Female Arthritis, Rheumatoid Humans Aged Treatment Outcome Biomarkers Young Adult Anti-Citrullinated Protein Antibodies Retrospective Studies
View on PubMed DOI

Digital-to-biological converter for on-demand production of biologics.

Nature biotechnology May 29, 2017
Manufacturing processes for biological molecules in the research laboratory have failed to keep pace with the rapid advances in automization and parellelization. We report the development of a digital-to-biological converter for fully automated, vers...
Equipment Design High-Throughput Nucleotide Sequencing Synthetic Biology Equipment Failure Analysis Biological Products Robotics Genetic Engineering Biopolymers
View on PubMed DOI

Computer-aided Dereplication and Structure Elucidation of Natural Products at the University of Reims.

Molecular informatics Apr 27, 2017
Natural product chemistry began in Reims, France, in a pharmacognosy research laboratory whose main emphasis was the isolation and identification of bioactive molecules, following the guidelines of chemotaxonomy. The structure elucidation of new comp...
Artificial Intelligence Plant Extracts Magnetic Resonance Spectroscopy Biological Products Chromatography, Liquid Molecular Structure France
View on PubMed DOI

Simultaneous Determination of Five Active Components in the Chinese Patent Medicine Niuhuang Jiangya Pill by HPLC-MS/MS.

Journal of AOAC International Dec 16, 2016
Niuhuang Jiangya (NHJY) pill is one of the well-known Chinese patent medicines in China used in the treatment of high blood pressure. The primary purpose of this study was to establish and validate a method using HPLC with tandem MS for the quality e...
Coumaric Acids China Tandem Mass Spectrometry Biological Products Drugs, Chinese Herbal Saponins Flavonoids Triterpenes Emodin Glucosides Monoterpenes Chromatography, High Pressure Liquid
View on PubMed DOI

Serum Interleukin-33 level in Saudi children with inflammatory bowel disease.

International journal of clinical and experimental pathology Dec 1, 2015
Interleukin-33 (IL-33) is a cytokine that belongs to the interleukin-1 family and has been shown to be associated with mucosal inflammation. The aim of this study was to determine the serum level of IL-33 in children with ulcerative colitis (UC) and ...
Male Severity of Illness Index Case-Control Studies Saudi Arabia Adolescent Child Enzyme-Linked Immunosorbent Assay Biomarkers Prognosis Inflammation Mediators Female Diagnosis, Differential Up-Regulation Cross-Sectional Studies Predictive Value of Tests Nephelometry and Turbidimetry Humans Age Factors C-Reactive Protein Crohn Disease Interleukin-33 Biological Products Colitis, Ulcerative Prospective Studies
View on PubMed

Neuroprotective effects of the Phellinus linteus ethyl acetate extract against H2O2-induced apoptotic cell death of SK-N-MC cells.

Nutrition research (New York, N.Y.) Nov 11, 2015
Numerous studies have suggested that neuronal cells are protected against oxidative stress-induced cell damage by antioxidants, such as polyphenolic compounds. Phellinus linteus (PL) has traditionally been used to treat various symptoms in East Asian...
Ethnopharmacology Medicine, Korean Traditional Phellinus Fruiting Bodies, Fungal Gene Expression Regulation, Enzymologic Oxidoreductases Nerve Tissue Proteins Acetates Polysaccharides Neurons Solvents MAP Kinase Signaling System Basidiomycota Neuroprotective Agents Apoptosis Biological Products Humans Polyphenols Oxidative Stress Brain Antioxidants Republic of Korea Plant Extracts Cell Line, Tumor
View on PubMed DOI

A Liquid-Handling Robot for Automated Attachment of Biomolecules to Microbeads.

Journal of laboratory automation Aug 26, 2015
Diagnostics, drug delivery, and other biomedical industries rely on cross-linking ligands to microbead surfaces. Microbead functionalization requires multiple steps of liquid exchange, incubation, and mixing, which are laborious and time intensive. A...
Robotics Microspheres Biological Products
View on PubMed DOI

Artificial neural network associated to UV/Vis spectroscopy for monitoring bioreactions in biopharmaceutical processes.

Bioprocess and biosystems engineering Jan 1, 2015
Currently, mammalian cells are the most utilized hosts for biopharmaceutical production. The culture media for these cell lines include commonly in their composition a pH indicator. Spectroscopic techniques are used for biopharmaceutical process moni...
Neural Networks, Computer Animals Culture Media Biological Products Hydrogen-Ion Concentration Cell Line Cricetinae Bioreactors Spectrophotometry, Ultraviolet
View on PubMed DOI

Advances in pharmacotherapy of juvenile idiopathic arthritis.

Expert opinion on pharmacotherapy Jun 1, 2025
INTRODUCTION: Juvenile Idiopathic Arthritis (JIA) is the most common chronic rheumatic disease in childhood. More therapeutic options are available for the treatment of JIA with more children achieving minimal active disease or inactive disease statu...
Humans Antirheumatic Agents Biomarkers Child Biological Products Arthritis, Juvenile
View on PubMed DOI
Popular Topics
Recent Journals