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Brain Neoplasms

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Utilizing machine learning to tailor radiotherapy and chemoradiotherapy for low-grade glioma patients.

PloS one
BACKGROUND: There is ongoing uncertainty about the effectiveness of various adjuvant treatments for low-grade gliomas (LGGs). Machine learning (ML) models that predict individual treatment effects (ITE) and provide treatment recommendations could hel...

Beyond hand-crafted features for pretherapeutic molecular status identification of pediatric low-grade gliomas.

Scientific reports
The use of targeted agents in the treatment of pediatric low-grade gliomas (pLGGs) relies on the determination of molecular status. It has been shown that genetic alterations in pLGG can be identified non-invasively using MRI-based radiomic features ...

Harnessing Deep Learning for Accurate Pathological Assessment of Brain Tumor Cell Types.

Journal of imaging informatics in medicine
Primary diffuse central nervous system large B-cell lymphoma (CNS-pDLBCL) and high-grade glioma (HGG) often present similarly, clinically and on imaging, making differentiation challenging. This similarity can complicate pathologists' diagnostic effo...

A deep-learning-based surrogate model for Monte-Carlo simulations of the linear energy transfer in primary brain tumor patients treated with proton-beam radiotherapy.

Physics in medicine and biology
This study explores the use of neural networks (NNs) as surrogate models for Monte-Carlo (MC) simulations in predicting the dose-averaged linear energy transfer (LET) of protons in proton-beam therapy based on the planned dose distribution and patien...

Neuro-XAI: Explainable deep learning framework based on deeplabV3+ and bayesian optimization for segmentation and classification of brain tumor in MRI scans.

Journal of neuroscience methods
The prevalence of brain tumor disorders is currently a global issue. In general, radiography, which includes a large number of images, is an efficient method for diagnosing these life-threatening disorders. The biggest issue in this area is that it t...

A multicenter study on deep learning for glioblastoma auto-segmentation with prior knowledge in multimodal imaging.

Cancer science
A precise radiotherapy plan is crucial to ensure accurate segmentation of glioblastomas (GBMs) for radiation therapy. However, the traditional manual segmentation process is labor-intensive and heavily reliant on the experience of radiation oncologis...

Training and Comparison of nnU-Net and DeepMedic Methods for Autosegmentation of Pediatric Brain Tumors.

AJNR. American journal of neuroradiology
BACKGROUND AND PURPOSE: Tumor segmentation is essential in surgical and treatment planning and response assessment and monitoring in pediatric brain tumors, the leading cause of cancer-related death among children. However, manual segmentation is tim...

BrainSegFounder: Towards 3D foundation models for neuroimage segmentation.

Medical image analysis
The burgeoning field of brain health research increasingly leverages artificial intelligence (AI) to analyze and interpret neuroimaging data. Medical foundation models have shown promise of superior performance with better sample efficiency. This wor...

Self-Supervised Image Denoising of Third Harmonic Generation Microscopic Images of Human Glioma Tissue by Transformer-Based Blind Spot (TBS) Network.

IEEE journal of biomedical and health informatics
Third harmonic generation (THG) microscopy shows great potential for instant pathology of brain tumor tissue during surgery. However, due to the maximal permitted exposure of laser intensity and inherent noise of the imaging system, the noise level o...

LightNet: A Novel Lightweight Convolutional Network for Brain Tumor Segmentation in Healthcare.

IEEE journal of biomedical and health informatics
Diagnosis, treatment planning, surveillance, and the monitoring of clinical trials for brain diseases all benefit greatly from neuroimaging-based tumor segmentation. Recently, Convolutional Neural Networks (CNNs) have demonstrated promising results i...