Journal of chemical information and modeling
May 26, 2025
Blood-brain barrier (BBB) permeability plays a crucial role in determining drug efficacy in the brain, with the brain-to-plasma unbound partition coefficient () recognized as a key parameter of BBB permeability in drug development. However, data are...
Different types of sports training can induce distinct changes in brain activity and function; however, it remains unclear if there are commonalities across various sports disciplines. Moreover, the relationship between these brain activity alteratio...
Biomedical physics & engineering express
May 22, 2025
Electroencephalography (EEG) is essential for studying infant brain activity but is highly susceptible to artifacts due to infants' movements and physiological variability. Manual artifact detection is labor-intensive and subjective, underscoring the...
The human brain is a dynamic system that is constantly learning. It employs a combination of various learning strategies to facilitate complex learning processes. However, implementing biological learning mechanisms into Spiking Neural Networks (SNNs...
Achieving general artificial intelligence (AGI) has long been a grand challenge in the field of AI, and brain-inspired computing is widely acknowledged as one of the most promising approaches to realize this goal. This paper introduces a novel brain-...
Journal of the American Chemical Society
May 21, 2025
Exploring the time-resolved dynamics of neurochemicals is essential for deciphering neuronal functions, intercellular communication, and neurophysiological or pathological mechanisms. However, the complex interplay among neurochemicals between neuroc...
Biomedical physics & engineering express
May 21, 2025
Alzheimer's disease (AD), a progressive neurodegenerative disorder, is the leading cause of dementia worldwide and remains incurable once it begins. Therefore, early and accurate diagnosis is essential for effective intervention. Leveraging recent ad...
Dementia spectrum disorders, characterized by progressive cognitive decline, pose a significant global health burden. Early screening and diagnosis are essential for timely and accurate treatment, improving patient outcomes and quality of life. This ...
BACKGROUND: Internet addiction (IA) refers to excessive internet use that causes cognitive impairment or distress. Understanding the neurophysiological mechanisms underpinning IA is crucial for enabling an accurate diagnosis and informing treatment a...
. Positron emission tomography (PET) is affected by statistical noise due to constraints on tracer dose and scan duration, impacting both diagnostic performance and quantitative accuracy. While deep learning-based PET denoising methods have been used...
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