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Breast Neoplasms

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Automated Quantification of HER2 Amplification Levels Using Deep Learning.

IEEE journal of biomedical and health informatics
HER2 assessment is necessary for patient selection in anti-HER2 targeted treatment. However, manual assessment of HER2 amplification is time-costly, labor-intensive, highly subjective and error-prone. Challenges in HER2 analysis in fluorescence in si...

DIFLF: A domain-invariant features learning framework for single-source domain generalization in mammogram classification.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Single-source domain generalization (SSDG) aims to generalize a deep learning (DL) model trained on one source dataset to multiple unseen datasets. This is important for the clinical applications of DL-based models to breast...

Breast cancer classification based on breast tissue structures using the Jigsaw puzzle task in self-supervised learning.

Radiological physics and technology
Self-supervised learning (SSL) has gained attention in the medical field as a deep learning approach utilizing unlabeled data. The Jigsaw puzzle task in SSL enables models to learn both features of images and the positional relationships within image...

Automatic image generation and stage prediction of breast cancer immunobiological through a proposed IHC-GAN model.

BMC medical imaging
Invasive breast cancer diagnosis and treatment planning require an accurate assessment of human epidermal growth factor receptor 2 (HER2) expression levels. While immunohistochemical techniques (IHC) are the gold standard for HER2 evaluation, their i...

Explainable attention based breast tumor segmentation using a combination of UNet, ResNet, DenseNet, and EfficientNet models.

Scientific reports
This study utilizes the Breast Ultrasound Image (BUSI) dataset to present a deep learning technique for breast tumor segmentation based on a modified UNet architecture. To improve segmentation accuracy, the model integrates attention mechanisms, such...

Machine learning Nomogram for Predicting endometrial lesions after tamoxifen therapy in breast Cancer patients.

Scientific reports
Objective Endometrial lesions are a frequent complication following breast cancer, and current diagnostic tools have limitations. This study aims to develop a machine learning-based nomogram model for predicting the early detection of endometrial les...

Insights into AI advances in immunohistochemistry for effective breast cancer treatment: a literature review of ER, PR, and HER2 scoring.

Current medical research and opinion
Breast cancer is a significant health challenge, with accurate and timely diagnosis being critical to effective treatment. Immunohistochemistry (IHC) staining is a widely used technique for the evaluation of breast cancer markers, but manual scoring ...

Self-interactive learning: Fusion and evolution of multi-scale histomorphology features for molecular traits prediction in computational pathology.

Medical image analysis
Predicting disease-related molecular traits from histomorphology brings great opportunities for precision medicine. Despite the rich information present in histopathological images, extracting fine-grained molecular features from standard whole slide...

Prototype Learning Guided Hybrid Network for Breast Tumor Segmentation in DCE-MRI.

IEEE transactions on medical imaging
Automated breast tumor segmentation on the basis of dynamic contrast-enhancement magnetic resonance imaging (DCE-MRI) has shown great promise in clinical practice, particularly for identifying the presence of breast disease. However, accurate segment...

Analyzing Secondary Cancer Risk: A Machine Learning Approach.

Asian Pacific journal of cancer prevention : APJCP
OBJECTIVE: Addressing the rising cancer rates through timely diagnosis and treatment is crucial. Additionally, cancer survivors need to understand the potential risk of developing secondary cancer (SC), which can be influenced by several factors incl...