AIMC Topic: Breast Neoplasms

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A Novel Effective Models for Identifying BRCA Patients and Optimizing Clinical Treatments.

Anti-cancer agents in medicinal chemistry
OBJECTIVE: This study aimed to develop an effective model that identifies high-risk breast cancer (BRCA) patients and optimizes clinical treatments.

ClinValAI: A framework for developing Cloud-based infrastructures for the External Clinical Validation of AI in Medical Imaging.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing
Artificial Intelligence (AI) algorithms showcase the potential to steer a paradigm shift in clinical medicine, especially medical imaging. Concerns associated with model generalizability and biases necessitate rigorous external validation of AI algor...

Deep Learning Applied to Diffusion-weighted Imaging for Differentiating Malignant from Benign Breast Tumors without Lesion Segmentation.

Radiology. Artificial intelligence
Purpose To evaluate and compare the performance of different artificial intelligence (AI) models in differentiating between benign and malignant breast tumors at diffusion-weighted imaging (DWI), including comparison with radiologist assessments. Mat...

Radiomic analysis of cohort-specific diagnostic errors in reading dense mammograms using artificial intelligence.

The British journal of radiology
OBJECTIVES: This study aims to investigate radiologists' interpretation errors when reading dense screening mammograms using a radiomics-based artificial intelligence approach.

Evaluation of machine learning algorithms and computational structural validation of CYP2D6 in predicting the therapeutic response to tamoxifen in breast cancer.

European review for medical and pharmacological sciences
OBJECTIVE: CYP2D6 plays a critical role in metabolizing tamoxifen into its active metabolite, endoxifen, which is crucial for its therapeutic effect in estrogen receptor-positive breast cancer. Single nucleotide polymorphisms (SNPs) in the CYP2D6 gen...

Monitoring Over Time of Pathological Complete Response to Neoadjuvant Chemotherapy in Breast Cancer Patients Through an Ensemble Vision Transformers-Based Model.

Cancer medicine
BACKGROUND: Morphological and vascular characteristics of breast cancer can change during neoadjuvant chemotherapy (NAC). Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI)-acquired pre- and mid-treatment quantitatively capture informatio...

Classification-based pathway analysis using GPNet with novel P-value computation.

Briefings in bioinformatics
Pathway analysis plays a critical role in bioinformatics, enabling researchers to identify biological pathways associated with various conditions by analyzing gene expression data. However, the rise of large, multi-center datasets has highlighted lim...

Comprehensive bioinformatics and machine learning analyses for breast cancer staging using TCGA dataset.

Briefings in bioinformatics
Breast cancer is an alarming global health concern, including a vast and varied set of illnesses with different molecular characteristics. The fusion of sophisticated computational methodologies with extensive biological datasets has emerged as an ef...

Development of an AI Platform for Advanced Breast Cancer Management.

Studies in health technology and informatics
This article explores the transition from a traditional histopathological examination system to an innovative platform using artificial intelligence (AI) for breast cancer detection from histopathological images in Burkina Faso. The existing system i...

Deep Learning Algorithms for Breast Cancer Detection in a UK Screening Cohort: As Stand-alone Readers and Combined with Human Readers.

Radiology
Background Deep learning (DL) algorithms have shown promising results in mammographic screening either compared to a single reader or, when deployed in conjunction with a human reader, compared with double reading. Purpose To externally validate the ...