Journal of clinical laboratory analysis
Nov 21, 2024
BACKGROUND: HER2-positive breast cancer (BC), a highly aggressive malignancy, has been treated with the targeted therapy inetetamab for metastatic cases. Inetetamab (Cipterbin) is a recently approved targeted therapy for HER2-positive metastatic BC, ...
BACKGROUND: Exosome small RNAs are believed to be involved in the pathogenesis of cancer, but their role in breast cancer is still unclear. This study utilized machine learning models to screen for key exosome small RNAs and analyzed and validated th...
Medical image classification requires labeled, task-specific datasets which are used to train deep learning networks de novo, or to fine-tune foundation models. However, this process is computationally and technically demanding. In language processin...
This study aims to investigate the feasibility of utilizing generative adversarial networks (GANs) to synthesize high-fidelity computed tomography (CT) images from lower-resolution MR images. The goal is to reduce patient exposure to ionizing radiati...
BACKGROUND AND OBJECTIVE: Detecting patients at high risk of occurrence of an Invasive Disease Event after a first diagnosis of breast cancer, such as recurrence, distant metastasis, contralateral tumor and second tumor, could support clinical decisi...
The study explored endocrine resistance by leveraging machine learning to establish the prognostic stratification of predicted Circulating tumor cells (CTCs), assessing its integration with circulating tumor DNA (ctDNA) features and contextually eval...
Breast mass segmentation plays a crucial role in early breast cancer detection and diagnosis, and while Convolutional Neural Networks (CNN) have been widely used for this task, their reliance on local receptive fields limits ability to capture long-r...
Early diagnosis of breast cancer is exceptionally important in signifying the treatment results, of women's health. The present study outlines a novel approach for analyzing breast cancer data by using the CatBoost classification model with a multi-l...
BACKGROUND: Breast cancer, characterized by its heterogeneity, is a leading cause of mortality among women. The study aims to develop a Machine Learning-Derived Liquid-Liquid Phase Separation (MDLS) model to enhance the prognostic accuracy and person...
BACKGROUND AND PURPOSE: Tumor bed (TB) is the residual cavity of resected tumor after surgery. Delineating TB from CT is crucial in generating clinical target volume for radiotherapy. Due to multiple surgical effects and low image contrast, segmentin...
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