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Carcinoma, Hepatocellular

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Data Centric Molecular Analysis and Evaluation of Hepatocellular Carcinoma Therapeutics Using Machine Intelligence-Based Tools.

Journal of gastrointestinal cancer
PURPOSE: Computational approaches have been used at different stages of drug development with the purpose of decreasing the time and cost of conventional experimental procedures. Lately, techniques mainly developed and applied in the field of artific...

Novel deep learning-based solution for identification of prognostic subgroups in liver cancer (Hepatocellular carcinoma).

BMC bioinformatics
BACKGROUND: Liver cancer (Hepatocellular carcinoma; HCC) prevalence is increasing and with poor clinical outcome expected it means greater understanding of HCC aetiology is urgently required. This study explored a deep learning solution to detect bio...

Deep learning radiomics based on contrast enhanced computed tomography predicts microvascular invasion and survival outcome in early stage hepatocellular carcinoma.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
OBJECTIVE: To evaluate the performance of a deep learning (DL)-based radiomics strategy on contrast-enhanced computed tomography (CT) to predict microvascular invasion (MVI) status and clinical outcomes, recurrence-free survival (RFS) and overall sur...

Supervised learning based on tumor imaging and biopsy transcriptomics predicts response of hepatocellular carcinoma to transarterial chemoembolization.

Cell reports. Medicine
Although transarterial chemoembolization (TACE) is the most widely used treatment for intermediate-stage, unresectable hepatocellular carcinoma (HCC), it is only effective in a subset of patients. In this study, we combine clinical, radiological, and...

Predicting microvascular invasion in hepatocellular carcinoma: a deep learning model validated across hospitals.

Cancer imaging : the official publication of the International Cancer Imaging Society
BACKGROUND: The accuracy of estimating microvascular invasion (MVI) preoperatively in hepatocellular carcinoma (HCC) by clinical observers is low. Most recent studies constructed MVI predictive models utilizing radiological and/or radiomics features ...

An artificial intelligence model to predict hepatocellular carcinoma risk in Korean and Caucasian patients with chronic hepatitis B.

Journal of hepatology
BACKGROUND & AIMS: Several models have recently been developed to predict risk of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B (CHB). Our aims were to develop and validate an artificial intelligence-assisted prediction model of...

An attention-based deep learning model for predicting microvascular invasion of hepatocellular carcinoma using an intra-voxel incoherent motion model of diffusion-weighted magnetic resonance imaging.

Physics in medicine and biology
The intra-voxel incoherent motion model of diffusion-weighted magnetic resonance imaging (IVIM-DWI) with a series of images with different-values has great potential as a tool for detecting, diagnosing, staging, and monitoring disease progression or ...

Identifying novel transcript biomarkers for hepatocellular carcinoma (HCC) using RNA-Seq datasets and machine learning.

BMC cancer
BACKGROUND: Hepatocellular carcinoma (HCC) is one of the leading causes of cancer death in the world owing to limitations in its prognosis. The current prognosis approaches include radiological examination and detection of serum biomarkers, however, ...