AIMC Topic: Carcinoma, Pancreatic Ductal
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Effectiveness of Radiomics-Based Machine Learning Models in Differentiating Pancreatitis and Pancreatic Ductal Adenocarcinoma: Systematic Review and Meta-Analysis.
Journal of medical Internet research
Jul 31, 2025
BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) and mass-forming pancreatitis (MFP) share similar clinical, laboratory, and imaging features, making accurate diagnosis challenging. Nevertheless, PDAC is highly malignant with a poor prognosis, whe...
Early neoplastic lesions of the pancreas: initiation, progression, and opportunities for precancer interception.
The Journal of clinical investigation
Jul 15, 2025
Pancreatic ductal adenocarcinoma (PDAC) is known to progress from one of two main precursor lesions: pancreatic intraepithelial neoplasia (PanIN) or intraductal papillary mucinous neoplasm (IPMN). The poor survival rates for patients with PDAC, even ...
Plasma and Urine Circulating Tumor DNA Methylation Profiles for Non-Invasive Pancreatic Ductal Adenocarcinoma Detection: Significant Findings in Plasma Only.
International journal of molecular sciences
May 22, 2025
Pancreatic ductal adenocarcinoma (PDAC) is a lethal malignancy with limited treatment options, and early detection remains challenging due to the lack of reliable non-invasive biomarkers. This study investigated plasma and urine circulating tumor deo...
Machine Learning to Predict Early Death Despite Pancreaticoduodenectomy.
The Journal of surgical research
Apr 26, 2025
INTRODUCTION: About 25% of patients undergoing pancreaticoduodenectomy (PD) for right-sided pancreatic ductal adenocarcinoma (PDAC) die within 1 y of diagnosis. These patients carry all the risks of significant morbidity with no survival advantage wh...
Novel CT radiomics models for the postoperative prediction of early recurrence of resectable pancreatic adenocarcinoma: A single-center retrospective study in China.
Journal of applied clinical medical physics
Apr 11, 2025
PURPOSE: To assess the predictive capability of CT radiomics features for early recurrence (ER) of pancreatic ductal adenocarcinoma (PDAC).
Preoperative assessment in lymph node metastasis of pancreatic ductal adenocarcinoma: a transformer model based on dual-energy CT.
World journal of surgical oncology
Apr 9, 2025
BACKGROUND: Deep learning(DL) models can improve significantly discrimination of lymph node metastasis(LNM) of pancreatic ductal adenocarcinoma(PDAC), but have not been systematically assessed.
Gap-App: A sex-distinct AI-based predictor for pancreatic ductal adenocarcinoma survival as a web application open to patients and physicians.
Cancer letters
Apr 4, 2025
In this study, using RNA-Seq gene expression data and advanced machine learning techniques, we identified distinct gene expression profiles between male and female pancreatic ductal adenocarcinoma (PDAC) patients. Building on this insight, we develop...
Development of Multiparametric Prognostic Models for Stereotactic Magnetic Resonance Guided Radiation Therapy of Pancreatic Cancers.
International journal of radiation oncology, biology, physics
Apr 2, 2025
PURPOSE: Stereotactic magnetic resonance guided adaptive radiation therapy (SMART) is a new option for local treatment of unresectable pancreatic ductal adenocarcinoma, showing interesting survival and local control (LC) results. Despite this, some p...
Development of PDAC diagnosis and prognosis evaluation models based on machine learning.
BMC cancer
Mar 20, 2025
BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is difficult to detect early and highly aggressive, often leading to poor patient prognosis. Existing serum biomarkers like CA19-9 are limited in early diagnosis, failing to meet clinical needs. Mac...
Stroma and lymphocytes identified by deep learning are independent predictors for survival in pancreatic cancer.
Scientific reports
Mar 19, 2025
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers known to humans. However, not all patients fare equally poor survival, and a minority of patients even survives advanced disease for months or years. Thus, there is a clinical ...
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