AIMC Topic: Causality

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Combining machine learning and propensity score weighting to estimate causal effects in multivalued treatments.

Journal of evaluation in clinical practice
RATIONALE, AIMS AND OBJECTIVES: Interventions with multivalued treatments are common in medical and health research; examples include comparing the efficacy of competing interventions and contrasting various doses of a drug. In recent years, there ha...

Combining machine learning and matching techniques to improve causal inference in program evaluation.

Journal of evaluation in clinical practice
RATIONALE, AIMS AND OBJECTIVES: Program evaluations often utilize various matching approaches to emulate the randomization process for group assignment in experimental studies. Typically, the matching strategy is implemented, and then covariate balan...

Transitive closure of subsumption and causal relations in a large ontology of radiological diagnosis.

Journal of biomedical informatics
The Radiology Gamuts Ontology (RGO)-an ontology of diseases, interventions, and imaging findings-was developed to aid in decision support, education, and translational research in diagnostic radiology. The ontology defines a subsumption (is_a) relati...

Prioritizing Clinically Relevant Copy Number Variation from Genetic Interactions and Gene Function Data.

PloS one
It is becoming increasingly necessary to develop computerized methods for identifying the few disease-causing variants from hundreds discovered in each individual patient. This problem is especially relevant for Copy Number Variants (CNVs), which can...

Value of information analysis for interventional and counterfactual Bayesian networks in forensic medical sciences.

Artificial intelligence in medicine
OBJECTIVES: Inspired by real-world examples from the forensic medical sciences domain, we seek to determine whether a decision about an interventional action could be subject to amendments on the basis of some incomplete information within the model,...

Neural networks with non-uniform embedding and explicit validation phase to assess Granger causality.

Neural networks : the official journal of the International Neural Network Society
A challenging problem when studying a dynamical system is to find the interdependencies among its individual components. Several algorithms have been proposed to detect directed dynamical influences between time series. Two of the most used approache...

Granger causality-based synaptic weights estimation for analyzing neuronal networks.

Journal of computational neuroscience
Granger causality (GC) analysis has emerged as a powerful analytical method for estimating the causal relationship among various types of neural activity data. However, two problems remain not very clear and further researches are needed: (1) The GC ...

Pulling back the curtain: the road from statistical estimand to machine-learning-based estimator for epidemiologists (no wizard required).

American journal of epidemiology
Epidemiologists increasingly use causal inference methods that rely on machine learning, as these approaches can relax unnecessary model specification assumptions. While deriving and studying asymptotic properties of such estimators is a task usually...

A meta-learning method for estimation of causal excursion effects to assess time-varying moderation.

Biometrics
Advances in wearable technologies and health interventions delivered by smartphones have greatly increased the accessibility of mobile health (mHealth) interventions. Micro-randomized trials (MRTs) are designed to assess the effectiveness of the mHea...

A Bayesian Approach to the G-Formula via Iterative Conditional Regression.

Statistics in medicine
In longitudinal observational studies with time-varying confounders, the generalized computation algorithm formula (g-formula) is a principled tool to estimate the average causal effect of a treatment regimen. However, the standard non-iterative g-fo...