BACKGROUND: Oral microbiota is a major etiological factor in the development of dental caries. Next-generation sequencing techniques have been widely used, generating vast amounts of data which is underexplored. The advancement of artificial intellig...
While exome and whole genome sequencing have transformed medicine by elucidating the genetic underpinnings of both rare and common complex disorders, its utility to predict clinical outcomes remains understudied. Here, we use artificial intelligence ...
BACKGROUND: Early diagnosis is crucial for reducing disability and improving long-term prognosis in patients with systemic Juvenile Idiopathic Arthritis (sJIA), but it remains a significant challenge. This study aims to identify non-invasive biomarke...
BACKGROUND: Height gain in children with growth disorders undergoing recombinant human growth hormone (rhGH) therapy shows considerable variability. Predicting treatment outcomes is essential for optimizing individualized treatment strategies.
Intravenous immunoglobulin (IVIG) has been established as the first-line therapy for Kawasaki disease (KD). However, approximately 10%-20% of pediatric patients exhibit IVIG resistance. Current machine learning (ML) models demonstrate suboptimal pred...
This study introduces a novel approach to dengue diagnostics by leveraging surface-enhanced Raman spectroscopy (SERS) coupled to machine learning. This method addresses the critical need for rapid and accurate identification of dengue virus (DENV) in...
BACKGROUND: Poly-victimization (PV), encompassing multiple forms of victimization including physical abuse, emotional maltreatment, neglect, and peer violence, poses a significant public health challenge among children, particularly in rural areas wi...
Pediatric gastroenteritis is a major reason for sickness and death among children worldwide, especially in places where healthcare and clean sanitation are scarce. Conventional methods of diagnosis overlook possible risks and seasonal trends, which r...
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