AIMC Topic: Cognitive Dysfunction

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Cortical graph neural network for AD and MCI diagnosis and transfer learning across populations.

NeuroImage. Clinical
Combining machine learning with neuroimaging data has a great potential for early diagnosis of mild cognitive impairment (MCI) and Alzheimer's disease (AD). However, it remains unclear how well the classifiers built on one population can predict MCI/...

Incorporating Conversational Strategies in a Social Robot to Interact with People with Dementia.

Dementia and geriatric cognitive disorders
BACKGROUND: Socially assistive robots (SARs) have the potential to assist nonpharmacological interventions based on verbal communication to support the care of persons with dementia (PwDs). However, establishing verbal communication with a PwD is cha...

Studying the Manifold Structure of Alzheimer's Disease: A Deep Learning Approach Using Convolutional Autoencoders.

IEEE journal of biomedical and health informatics
Many classical machine learning techniques have been used to explore Alzheimer's disease (AD), evolving from image decomposition techniques such as principal component analysis toward higher complexity, non-linear decomposition algorithms. With the a...

Machine learning identifies unaffected first-degree relatives with functional network patterns and cognitive impairment similar to those of schizophrenia patients.

Human brain mapping
Schizophrenia (SCZ) patients and their unaffected first-degree relatives (FDRs) share similar functional neuroanatomy. However, it remains largely unknown to what extent unaffected FDRs with functional neuroanatomy patterns similar to patients can be...

A hybrid Convolutional and Recurrent Neural Network for Hippocampus Analysis in Alzheimer's Disease.

Journal of neuroscience methods
BACKGROUND: Hippocampus is one of the first structures affected by neurodegenerative diseases such as Alzheimer's disease (AD) and mild cognitive impairment (MCI). Hippocampal atrophy can be evaluated in terms of hippocampal volumes and shapes using ...

Deep learning only by normal brain PET identify unheralded brain anomalies.

EBioMedicine
BACKGROUND: Recent deep learning models have shown remarkable accuracy for the diagnostic classification. However, they have limitations in clinical application due to the gap between the training cohorts and real-world data. We aimed to develop a mo...

Machine learning approaches to studying the role of cognitive reserve in conversion from mild cognitive impairment to dementia.

International journal of geriatric psychiatry
OBJECTIVES: The overall aim of the present study was to explore the role of cognitive reserve (CR) in the conversion from mild cognitive impairment (MCI) to dementia. We used traditional and machine learning (ML) techniques to compare converter and n...

Detection of mild cognitive impairment in a community-dwelling population using quantitative, multiparametric MRI-based classification.

Human brain mapping
Early and accurate mild cognitive impairment (MCI) detection within a heterogeneous, nonclinical population is needed to improve care for persons at risk of developing dementia. Magnetic resonance imaging (MRI)-based classification may aid early diag...

Hybrid multivariate pattern analysis combined with extreme learning machine for Alzheimer's dementia diagnosis using multi-measure rs-fMRI spatial patterns.

PloS one
BACKGROUND: Early diagnosis of Alzheimer's disease (AD) and Mild Cognitive Impairment (MCI) is essential for timely treatment. Machine learning and multivariate pattern analysis (MVPA) for the diagnosis of brain disorders are explicitly attracting at...