AIMC Topic: Cognitive Dysfunction

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A Deep Learning Model to Predict a Diagnosis of Alzheimer Disease by Using F-FDG PET of the Brain.

Radiology
Purpose To develop and validate a deep learning algorithm that predicts the final diagnosis of Alzheimer disease (AD), mild cognitive impairment, or neither at fluorine 18 (F) fluorodeoxyglucose (FDG) PET of the brain and compare its performance to t...

Effective feature learning and fusion of multimodality data using stage-wise deep neural network for dementia diagnosis.

Human brain mapping
In this article, the authors aim to maximally utilize multimodality neuroimaging and genetic data for identifying Alzheimer's disease (AD) and its prodromal status, Mild Cognitive Impairment (MCI), from normal aging subjects. Multimodality neuroimagi...

Learning to Detect Cognitive Impairment through Digital Games and Machine Learning Techniques.

Methods of information in medicine
OBJECTIVE: Alzheimer's disease (AD) is one of the most prevalent diseases among the adult population. The early detection of Mild Cognitive Impairment (MCI), which may trigger AD, is essential to slow down the cognitive decline process.

Instance-Based Representation Using Multiple Kernel Learning for Predicting Conversion to Alzheimer Disease.

International journal of neural systems
The early detection of Alzheimer's disease and quantification of its progression poses multiple difficulties for machine learning algorithms. Two of the most relevant issues are related to missing data and results interpretability. To deal with both ...

Temporal Correlation Structure Learning for MCI Conversion Prediction.

Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention
In Alzheimer's research, Mild Cognitive Impairment (MCI) is an important intermediate stage between normal aging and Alzheimer's. How to distinguish MCI samples that finally convert to AD from those do not is an essential problem in the prevention an...

A Novel Deep Learning Framework on Brain Functional Networks for Early MCI Diagnosis.

Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention
Although alternations of brain functional networks (BFNs) derived from resting-state functional magnetic resonance imaging (rs-fMRI) have been considered as promising biomarkers for early Alzheimer's disease (AD) diagnosis, it is still challenging to...

Using high-dimensional machine learning methods to estimate an anatomical risk factor for Alzheimer's disease across imaging databases.

NeuroImage
INTRODUCTION: The main goal of this work is to investigate the feasibility of estimating an anatomical index that can be used as an Alzheimer's disease (AD) risk factor in the Women's Health Initiative Magnetic Resonance Imaging Study (WHIMS-MRI) usi...