AIMC Topic:
Computer Simulation

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Trunk pitch oscillations for energy trade-offs in bipedal running birds and robots.

Bioinspiration & biomimetics Mar 31, 2020
Bipedal animals have diverse morphologies and advanced locomotion abilities. Terrestrial birds, in particular, display agile, efficient, and robust running motion, in which they exploit the interplay between the body segment masses and moment of iner...
Models, Biological Animals Locomotion Birds Robotics Computer Simulation Biomechanical Phenomena
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How could artificial intelligence aid in the fight against coronavirus?

Expert review of anti-infective therapy Mar 29, 2020
Pneumonia, Viral SARS-CoV-2 Pandemics Drug Evaluation, Preclinical Humans COVID-19 Viral Vaccines Coronavirus Infections Drug Discovery Artificial Intelligence Computer Simulation Betacoronavirus
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Grid-Based Mobile Robot Path Planning Using Aging-Based Ant Colony Optimization Algorithm in Static and Dynamic Environments.

Sensors (Basel, Switzerland) Mar 28, 2020
Planning an optimal path for a mobile robot is a complicated problem as it allows the mobile robots to navigate autonomously by following the safest and shortest path between starting and goal points. The present work deals with the design of intelli...
Humans Computers, Handheld Artificial Intelligence Computer Systems Algorithms Robotics Computer Simulation Motion
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Policy gradient optimization of controllers for natural dynamic mono-pedal gait.

Bioinspiration & biomimetics Mar 25, 2020
We have previously suggested a biologically-inspired natural dynamic controller for biped locomotion, which applies torque pulses to the different joints at particular phases of an internal phase variable. The parameters of the controller, including ...
Humans Algorithms Equipment Design Gait Leg Computer Simulation Biomechanical Phenomena Robotics
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Using Machine Learning Methods and Structural Alerts for Prediction of Mitochondrial Toxicity.

Molecular informatics Mar 23, 2020
Over the last few years more and more organ and idiosyncratic toxicities were linked to mitochondrial toxicity. Despite well-established assays, such as the seahorse and Glucose/Galactose assay, an in silico approach to mitochondrial toxicity is stil...
Machine Learning Algorithms Drug-Related Side Effects and Adverse Reactions Databases, Chemical Quantitative Structure-Activity Relationship Computer Simulation Drug Discovery Mitochondria
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Reporting quality of studies using machine learning models for medical diagnosis: a systematic review.

BMJ open Mar 23, 2020
AIMS: We conducted a systematic review assessing the reporting quality of studies validating models based on machine learning (ML) for clinical diagnosis, with a specific focus on the reporting of information concerning the participants on which the ...
Machine Learning Diagnosis, Computer-Assisted Humans Research Design Computer Simulation
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Computational Models Using Multiple Machine Learning Algorithms for Predicting Drug Hepatotoxicity with the DILIrank Dataset.

International journal of molecular sciences Mar 19, 2020
Drug-induced liver injury (DILI) remains one of the challenges in the safety profile of both authorized and candidate drugs, and predicting hepatotoxicity from the chemical structure of a substance remains a task worth pursuing. Such an approach is c...
Algorithms Databases, Factual Prognosis Humans Computer Simulation Drug-Related Side Effects and Adverse Reactions Models, Theoretical Machine Learning Quantitative Structure-Activity Relationship Chemical and Drug Induced Liver Injury
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SAEROF: an ensemble approach for large-scale drug-disease association prediction by incorporating rotation forest and sparse autoencoder deep neural network.

Scientific reports Mar 18, 2020
Drug-disease association is an important piece of information which participates in all stages of drug repositioning. Although the number of drug-disease associations identified by high-throughput technologies is increasing, the experimental methods ...
Humans Neural Networks, Computer Machine Learning Algorithms Databases, Factual Computer Simulation Support Vector Machine ROC Curve Area Under Curve Obesity Stomach Neoplasms Lung Neoplasms Anti-Obesity Agents Antineoplastic Agents Computational Biology
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Concurrent, face, content, and construct validity of the RobotiX Mentor simulator for robotic basic skills.

The international journal of medical robotics + computer assisted surgery : MRCAS Mar 14, 2020
OBJECTIVES: To assess several criteria, such as concurrent, face, content, and construct validity of the RobotiX Mentor (RXM) simulator for basic robotic skills and to compare virtual and actual dry lab dome.
Mentors Robotics Robotic Surgical Procedures Prospective Studies Computer Simulation Humans Clinical Competence
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Machine learning prediction of oncology drug targets based on protein and network properties.

BMC bioinformatics Mar 14, 2020
BACKGROUND: The selection and prioritization of drug targets is a central problem in drug discovery. Computational approaches can leverage the growing number of large-scale human genomics and proteomics data to make in-silico target identification, r...
Proteins Area Under Curve Antineoplastic Agents Humans Protein Interaction Maps Machine Learning Genomics Computer Simulation Drug Discovery
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