AIMC Topic: Computer Simulation

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Surrogate modeling for time-dependent reliability analysis of robotic manipulator trajectories.

PloS one
The kinematic reliability analysis of robotic manipulators is crucial due to uncertainties such as joint variations, manufacturing tolerances, and external disturbances. Traditional methods often rely on analytical techniques that struggle with nonli...

Synthetic Tabular Data Generation Under Horizontal Federated Learning Environments in Acute Myeloid Leukemia: Case-Based Simulation Study.

JMIR medical informatics
BACKGROUND: Data scarcity and dispersion pose significant obstacles in biomedical research, particularly when addressing rare diseases. In such scenarios, synthetic data generation (SDG) has emerged as a promising path to mitigate the first issue. Co...

Collective motion model inspired by fish school based on deep attention mechanism.

Bioinspiration & biomimetics
Collective intelligence in biological groups can be employed to inspire the control of artificial complex systems, such as swarm robotics. However, modeling for the social interactions between individuals is still a challenging task. Without loss of ...

In silico purification improves DNA methylation-based classification rates of pediatric low-grade gliomas.

Acta neuropathologica
DNA methylation-based classification using the Heidelberg Classifier is a state-of-the-art data-driven method for molecular diagnosis of central nervous system (CNS) tumors. However, many pediatric low-grade glioma (pLGG) samples fail to yield a conf...

Accelerating antibody development: sequence and structure-based models for predicting developability properties via size exclusion chromatography.

mAbs
Experimental screening for biopharmaceutical developability properties typically relies on resource-intensive, and time-consuming assays such as size exclusion chromatography (SEC). This study highlights the potential of in silico models to accelerat...

Fuzzy and fractional analysis of cancer tumor dynamics with depression effects on chemotherapy.

Scientific reports
Cancer is a complex and heterogeneous condition marked by the unchecked growth and dissemination of abnormal cells, posing significant challenges in detection, treatment, and patient care. As one of the leading global causes of death, a deep understa...

Novel antimicrobial peptide HFIAP-1 mutant as a β-lactamase inhibitor against extended-spectrum β-lactamases of Escherichia coli: a comprehensive in-silico approach.

Archives of microbiology
Extended-spectrum β-lactamases in Escherichia coli poses a significant threat for clinicians in tertiary healthcare settings, rendering treatments ineffective with newer β-lactam-β-lactamase inhibitors combinations. To overcome this, the present stud...

Neural CRNs: A Natural Implementation of Learning in Chemical Reaction Networks.

ACS synthetic biology
Molecular circuits capable of autonomous learning could unlock novel applications in fields such as bioengineering and synthetic biology. To this end, existing chemical implementations of neural computing have primarily relied on emulating discrete-l...

ADPO: automatic-differentiation-assisted parametric optimization.

Journal of pharmacokinetics and pharmacodynamics
Automatic differentiation (AD), a key method for accurately and efficiently computing derivatives in modern machine learning, is now implemented in Phoenix® NLME™ 8.6 for the first time and applied to the first-order conditional estimation extended l...

Experimental exploration of artificial intelligence and ADAMS simulation technology in the teaching of vertical hoop upward throw in rhythmic gymnastics.

PloS one
Currently, rhythmic gymnastics teaching mainly focuses on traditional techniques and cannot break through issues such as blind spots in the coordination training between apparatus and body. In the academic field, research results are still dominated ...