AIMC Topic: COVID-19

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Detection of S1 spike protein in CD16+ monocytes up to 245 days in SARS-CoV-2-negative post-COVID-19 vaccine syndrome (PCVS) individuals.

Human vaccines & immunotherapeutics
Despite over 13 billion SARS-CoV-2 vaccine doses administered globally, persistent post-vaccination symptoms, termed post-COVID-19 vaccine syndrome (PCVS), resemble post-acute sequelae of COVID-19 (PASC). Symptoms like cardiac, vascular, and neurolog...

Applications of artificial intelligence and nanotechnology in vaccine development.

International journal of pharmaceutics
Vaccines have long been crucial in safeguarding public health by preventing and controlling infectious diseases. However, traditional vaccine development methods face challenges in efficiency, cost, and response time to emerging pathogens. Recent pro...

Propofol-associated Hypertriglyceridemia: Development and Multicenter Validation of a Machine-Learning-Based Prediction Tool.

Journal of intensive care medicine
To develop and validate an explainable machine learning (ML) tool to help clinicians predict the risk of propofol-associated hypertriglyceridemia in critically ill patients receiving propofol sedation. Patients from 11 intensive care units (ICUs) a...

Prediction of mortality in cancer patients with COVID-19 using machine learning methods.

Medicine
This study aimed to predict mortality in cancer patients diagnosed with COVID-19 using machine learning (ML) algorithms and identify the clinical and laboratory parameters associated with mortality. Demographic, clinical, and laboratory data of cance...

Optimizing Antiviral Stockpiles for Pandemic Response: A Strategic Framework.

The Journal of infectious diseases
Influenza antiviral stockpiling represents a critical component of pandemic preparedness, yet evolving challenges demand new approaches to this strategic imperative. The Strategic National Stockpile's target of maintaining antiviral courses for 25% o...

β-lactam resistance: epidemiological trends, molecular drivers, and innovative control strategies in the post-pandemic era.

Clinical microbiology reviews
SUMMARY () is a major human pathogen that can cause severe diseases such as meningitis and bacteremia. β-lactam antibiotics are the most essential antimicrobial agents for treating infections, but the resistance has become a significant challenge in...

Designing Supportive Dashboards for Crisis Response to Protect Vulnerable Populations: A Qualitative Study.

Studies in health technology and informatics
INTRODUCTION: The COVID-19 pandemic exposed both direct and collateral health impacts especially on vulnerable populations, underscoring the need for more targeted and equitable crisis response strategies. Health-related dashboards could support bett...

Investigating heterogeneous effects of an expanded methadone access policy with opioid treatment program retention: a Rhode Island population-based retrospective cohort study.

American journal of epidemiology
Following federal regulatory changes during the COVID-19 pandemic, Rhode Island expanded methadone access for opioid treatment programs (OTPs) in March 2020. The policy, which permitted take-home dosing for patients, contrasted with longstanding rest...

Machine learning insights on the effectiveness of non-pharmaceutical interventions against COVID-19 in Nigeria.

International health
BACKGROUND: The lack of effective pharmacological measures during the early phase of the COVID-19 pandemic prompted the implementation of non-pharmaceutical interventions (NPIs) as initial mitigation strategies. The impact of these NPIs on COVID-19 i...