AIMC Topic: GPI-Linked Proteins

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Comprehensive analysis and experimental validation of BST1 as a novel diagnostic biomarker for pediatric sepsis using multiple machine learning algorithms.

European journal of pediatrics Jun 25, 2025
Bone marrow stromal cell antigen-1 (BST1) expression is elevated in a variety of human diseases, but its relationship with pediatric sepsis is unclear. This study aimed to investigate the expression of BST1 in pediatric sepsis patients and its value ...
Sepsis Adolescent Child, Preschool Child Female Male Infant GPI-Linked Proteins Receptors, Cell Surface Isoantigens ADP-ribosyl Cyclase ROC Curve Enzyme-Linked Immunosorbent Assay Antigens, CD Algorithms Humans Biomarkers Machine Learning
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Elevated Plasma Levels of MT4-MMP and MT6-MMP; A New Observation in Patients with Thyroid Nodules.

Archives of Iranian medicine Jun 1, 2023
BACKGROUND: Based on the critical role of MT4-MMP and MT6-MMP in carcinogenesis, we focused on MT4-MMP and MT6-MMP circulating levels in patients with thyroid nodules.
Matrix Metalloproteinases, Membrane-Associated Carcinogenesis GPI-Linked Proteins Matrix Metalloproteinase 17 Humans Thyroid Neoplasms Thyroid Nodule
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8-Hydroxy-2'-deoxyguanosine as a Discriminatory Biomarker for Early Detection of Breast Cancer.

Clinical breast cancer Dec 21, 2018
BACKGROUND: Breast cancer (BC) is one of the most prevalent and reported cancers among Saudi women. Detection of BC in the early invasive stage (stages I, II) has an advantage in treating patients over detection in the late invasive stage (stages III...
Humans Female Carcinoembryonic Antigen Biomarkers, Tumor Postmenopause Sensitivity and Specificity Case-Control Studies Early Detection of Cancer Mucin-1 Breast Neoplasms 8-Hydroxy-2'-Deoxyguanosine Risk GPI-Linked Proteins
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Serum Levels of Visfatin, Omentin and Irisin in Patients with End-Stage Lung Disease Before and After Lung Transplantation.

Annals of transplantation Dec 26, 2017
BACKGROUND The aim of this study was to investigate serum concentrations of visfatin, irisin, and omentin in patients with end-stage lung diseases (ESLD) before and after lung transplantation (LTx) and to find relationship between adipokines levels a...
Postoperative Period Lectins Cytokines Female Body Mass Index Humans Male Idiopathic Pulmonary Fibrosis Young Adult Adolescent Middle Aged Nicotinamide Phosphoribosyltransferase Adult Lung Transplantation Treatment Outcome Fibronectins Pulmonary Disease, Chronic Obstructive GPI-Linked Proteins Cystic Fibrosis
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PSCA rs1045531 Polymorphism and the Risk of Prostate Cancer in a Chinese Population Undergoing Prostate Biopsy.

Technology in cancer research & treatment Nov 14, 2017
BACKGROUND AND PURPOSE: This study explored the association between a single-nucleotide polymorphism of prostate stem cell antigen and prostate cancer in Chinese patients undergoing prostate biopsy.
Neoplasm Grading Prostate Biopsy Male Humans GPI-Linked Proteins Neoplasm Proteins Genetic Predisposition to Disease Genotype Middle Aged Risk Factors Prostatic Neoplasms Genetic Association Studies Aged Polymorphism, Single Nucleotide Prostate-Specific Antigen Antigens, Neoplasm
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Development of 3D-QSAR Model for Acetylcholinesterase Inhibitors Using a Combination of Fingerprint, Molecular Docking, and Structure-Based Pharmacophore Approaches.

Toxicological sciences : an official journal of the Society of Toxicology Jul 21, 2015
Acetylcholinesterase (AChE), a serine hydrolase vital for regulating the neurotransmitter acetylcholine in animals, has been used as a target for drugs and pesticides. With the increasing availability of AChE crystal structures, with or without ligan...
Expert Systems Catalytic Domain Molecular Conformation Quantitative Structure-Activity Relationship Ligands Acetylcholinesterase Cholinesterase Inhibitors Binding Sites Peptide Mapping Nootropic Agents Imaging, Three-Dimensional Computational Biology Databases, Protein GPI-Linked Proteins Artificial Intelligence Insecticides Animals Nerve Tissue Proteins Molecular Docking Simulation Humans Models, Molecular
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Detection of S1 spike protein in CD16+ monocytes up to 245 days in SARS-CoV-2-negative post-COVID-19 vaccine syndrome (PCVS) individuals.

Human vaccines & immunotherapeutics Dec 1, 2025
Despite over 13 billion SARS-CoV-2 vaccine doses administered globally, persistent post-vaccination symptoms, termed post-COVID-19 vaccine syndrome (PCVS), resemble post-acute sequelae of COVID-19 (PASC). Symptoms like cardiac, vascular, and neurolog...
Humans COVID-19 Cytokines Female Monocytes Male GPI-Linked Proteins Middle Aged Receptors, IgG COVID-19 Vaccines SARS-CoV-2 Spike Glycoprotein, Coronavirus Aged Adult
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