AIMC Topic: Critical Illness

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Machine learning versus physicians' prediction of acute kidney injury in critically ill adults: a prospective evaluation of the AKIpredictor.

Critical care (London, England)
BACKGROUND: Early diagnosis of acute kidney injury (AKI) is a major challenge in the intensive care unit (ICU). The AKIpredictor is a set of machine-learning-based prediction models for AKI using routinely collected patient information, and accessibl...

A deep learning model for real-time mortality prediction in critically ill children.

Critical care (London, England)
BACKGROUND: The rapid development in big data analytics and the data-rich environment of intensive care units together provide unprecedented opportunities for medical breakthroughs in the field of critical care. We developed and validated a machine l...

Intelligent ICU for Autonomous Patient Monitoring Using Pervasive Sensing and Deep Learning.

Scientific reports
Currently, many critical care indices are not captured automatically at a granular level, rather are repetitively assessed by overburdened nurses. In this pilot study, we examined the feasibility of using pervasive sensing technology and artificial i...

DeepSOFA: A Continuous Acuity Score for Critically Ill Patients using Clinically Interpretable Deep Learning.

Scientific reports
Traditional methods for assessing illness severity and predicting in-hospital mortality among critically ill patients require time-consuming, error-prone calculations using static variable thresholds. These methods do not capitalize on the emerging a...

A minimal set of physiomarkers in continuous high frequency data streams predict adult sepsis onset earlier.

International journal of medical informatics
PURPOSE: Sepsis is a life-threatening condition with high mortality rates and expensive treatment costs. To improve short- and long-term outcomes, it is critical to detect at-risk sepsis patients at an early stage.

Validation of Prediction Models for Critical Care Outcomes Using Natural Language Processing of Electronic Health Record Data.

JAMA network open
IMPORTANCE: Accurate prediction of outcomes among patients in intensive care units (ICUs) is important for clinical research and monitoring care quality. Most existing prediction models do not take full advantage of the electronic health record, usin...

Vitamin D in the ICU: More sun for critically ill adult patients?

Nutrition (Burbank, Los Angeles County, Calif.)
Critical illness in patients is characterized by systemic inflammation and oxidative stress. Vitamin D has a myriad of biological functions relevant to this population, including immunomodulation by the alteration of cytokine production and nuclear f...

Low vitamin D at ICU admission is associated with cancer, infections, acute respiratory insufficiency, and liver failure.

Nutrition (Burbank, Los Angeles County, Calif.)
OBJECTIVES: Vitamin D deficiency may be associated with comorbidities and poor prognosis. However, this association in patients in the intensive care unit (ICU) has not been fully elucidated. The aim of this study was to investigate whether the serum...

Comparison of 2 Natural Language Processing Methods for Identification of Bleeding Among Critically Ill Patients.

JAMA network open
IMPORTANCE: To improve patient safety, health care systems need reliable methods to detect adverse events in large patient populations. Events are often described in clinical notes, rather than structured data, which make them difficult to identify o...