AI Medical Compendium Topic

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Data Interpretation, Statistical

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Dendritic spine classification using shape and appearance features based on two-photon microscopy.

Journal of neuroscience methods
BACKGROUND: Neuronal morphology and function are highly coupled. In particular, dendritic spine morphology is strongly governed by the incoming neuronal activity. The first step towards understanding the structure-function relationships is to classif...

Guidelines for Developing and Reporting Machine Learning Predictive Models in Biomedical Research: A Multidisciplinary View.

Journal of medical Internet research
BACKGROUND: As more and more researchers are turning to big data for new opportunities of biomedical discoveries, machine learning models, as the backbone of big data analysis, are mentioned more often in biomedical journals. However, owing to the in...

Targeted Maximum Likelihood Estimation for Causal Inference in Observational Studies.

American journal of epidemiology
Estimation of causal effects using observational data continues to grow in popularity in the epidemiologic literature. While many applications of causal effect estimation use propensity score methods or G-computation, targeted maximum likelihood esti...

Revealing unobserved factors underlying cortical activity with a rectified latent variable model applied to neural population recordings.

Journal of neurophysiology
The activity of sensory cortical neurons is not only driven by external stimuli but also shaped by other sources of input to the cortex. Unlike external stimuli, these other sources of input are challenging to experimentally control, or even observe,...

Tackling Missing Data in Community Health Studies Using Additive LS-SVM Classifier.

IEEE journal of biomedical and health informatics
Missing data is a common issue in community health and epidemiological studies. Direct removal of samples with missing data can lead to reduced sample size and information bias, which deteriorates the significance of the results. While data imputatio...

Automatic Construction and Global Optimization of a Multisentiment Lexicon.

Computational intelligence and neuroscience
Manual annotation of sentiment lexicons costs too much labor and time, and it is also difficult to get accurate quantification of emotional intensity. Besides, the excessive emphasis on one specific field has greatly limited the applicability of doma...

Convolutional Deep Belief Networks for Single-Cell/Object Tracking in Computational Biology and Computer Vision.

BioMed research international
In this paper, we propose deep architecture to dynamically learn the most discriminative features from data for both single-cell and object tracking in computational biology and computer vision. Firstly, the discriminative features are automatically ...

An efficient automatic workload estimation method based on electrodermal activity using pattern classifier combinations.

International journal of psychophysiology : official journal of the International Organization of Psychophysiology
Automatic workload estimation has received much attention because of its application in error prevention, diagnosis, and treatment of neural system impairment. The development of a simple but reliable method using minimum number of psychophysiologica...