BACKGROUND: Many ontologies have been developed in biology and these ontologies increasingly contain large volumes of formalized knowledge commonly expressed in the Web Ontology Language (OWL). Computational access to the knowledge contained within t...
BACKGROUND: The proliferation of the scientific literature in the field of biomedicine makes it difficult to keep abreast of current knowledge, even for domain experts. While general Web search engines and specialized information retrieval (IR) syste...
Data from the electronic medical record comprise numerous structured but uncoded elements, which are not linked to standard terminologies. Reuse of such data for secondary research purposes has gained in importance recently. However, the identificati...
Journal of bioinformatics and computational biology
Jan 11, 2015
Molecular events normally have significant meanings since they describe important biological interactions or alternations such as binding of a protein. As a crucial step of biological event extraction, event trigger identification has attracted much ...
Regulatory toxicology and pharmacology : RTP
Dec 26, 2014
(Quantitative) structure activity relationship [(Q)SAR] modeling is the primary tool used to evaluate the mutagenic potential associated with drug impurities. General recommendations regarding the use of (Q)SAR in regulatory decision making have rece...
BACKGROUND: LinkRbrain is an open-access web platform for multi-scale data integration and visualization of human brain data. This platform integrates anatomical, functional, and genetic knowledge produced by the scientific community.
Journal of racial and ethnic health disparities
Dec 16, 2014
OBJECTIVE: To investigate the clinical characteristics and treatment patterns for African-American (AA) men with low-risk prostate cancer (PCa) using a national, population-based dataset.
OBJECTIVE: This work addresses the theoretical description and experimental evaluation of a new feature selection method (named uFilter). The uFilter improves the Mann-Whitney U-test for reducing dimensionality and ranking features in binary classifi...
INTRODUCTION: An increasing number of obese patients (body mass index [BMI] >30 kg/m(2)]) with localized prostate cancer are presenting as candidates for robot-assisted radical prostatectomy (RARP), which can be carried out using the transperitoneal ...
Controlled clinical trials are usually supported with an in-front data aggregation system, which supports the storage of relevant information according to the trial context within a highly structured environment. In contrast to the documentation of c...
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