Protein-protein interactions (PPIs) play an important role in the life activities of organisms. With the availability of large amounts of protein sequence data, PPIs prediction methods have attracted increasing attention. A variety of protein sequenc...
Oral surgery, oral medicine, oral pathology and oral radiology
Jun 6, 2019
OBJECTIVE: The aim of this study was to investigate whether a deep learning object detection technique can automatically detect and classify radiolucent lesions in the mandible on panoramic radiographs.
BACKGROUND: A prerequisite for many eye tracking and video-oculography (VOG) methods is an accurate localization of the pupil. Several existing techniques face challenges in images with artifacts and under naturalistic low-light conditions, e.g. with...
Survival analyses of populations and the establishment of prognoses for individual patients are important activities in the practice of medicine. Standard survival models, such as the Cox proportional hazards model, require extensive feature engineer...
Alternative polyadenylation (APA) is a major driver of transcriptome diversity in human cells. Here, we use deep learning to predict APA from DNA sequence alone. We trained our model (APARENT, APA REgression NeT) on isoform expression data from over ...
BACKGROUND: Wearable devices have evolved as screening tools for atrial fibrillation (AF). A photoplethysmographic (PPG) AF detection algorithm was developed and applied to a convenient smartphone-based device with good accuracy. However, patients wi...
International journal of molecular sciences
Jun 6, 2019
Structure-based drug design is becoming an essential tool for faster and more cost-efficient lead discovery relative to the traditional method. Genomic, proteomic, and structural studies have provided hundreds of new targets and opportunities for fut...
BACKGROUND: The limitations of traditional computer-aided detection (CAD) systems for mammography, the extreme importance of early detection of breast cancer and the high impact of the false diagnosis of patients drive researchers to investigate deep...
Artificial neural networks, as a specific approach towards artificial intelligence (AI), can open up a variety of new perspectives for endoscopy, such as automated lesion detection and the precise prediction of a lesion's histology by its endoscopic ...
We have attempted to reproduce the results in Development and validation of a deep learning algorithm for detection of diabetic retinopathy in retinal fundus photographs, published in JAMA 2016; 316(22), using publicly available data sets. We re-impl...
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