PURPOSE OF REVIEW: This review examines recent evidence for the effectiveness of telehealth in treating Post-Traumatic Stress Disorder (PTSD), Major Depressive Disorder (MDD), alcohol use disorder, and insomnia in military veterans and active-duty se...
Migraine is a complex neurological disorder with substantial heritability, yet genome-wide association studies (GWAS) have explained only a fraction of its genetic component. We developed InsightGWAS, a Transformer-based model, to enhance genetic dis...
Biomedical physics & engineering express
Dec 10, 2025
Major Depressive Disorder (MDD) diagnosis through Electroencephalography (EEG) is hindered by the non-stationary characteristics of neural oscillations and the limited adaptability of conventional classification frameworks. Static ensemble models, wh...
OBJECTIVE: Neuropsychiatric disorders are characterized by high complexity and comorbidity, imposing a substantial burden on both patients and society. However, their elusive pathogenic mechanisms impede accurate clinical diagnosis and effective inte...
This study investigates the shared molecular mechanisms between major depressive disorder (MDD) and systemic lupus erythematosus (SLE) through integrated bioinformatics analysis. Analysis of multiple GEO datasets identified 23 common differentially e...
The standard assessment of mental health typically involves clinical interviews conducted by highly trained clinicians. While effective, this approach faces substantial limitations, including high costs, high clinician workload, variability in expert...
BACKGROUND: Depression exhibits significant heterogeneity in antidepressant treatment response. This study aimed to develop an Electroencephalography (EEG)-based machine learning model integrating multidimensional features to predict selective seroto...
Depression is a significant public health issue, consistently ranking among the leading causes of mortality, reduced quality of life, and economic burden. Despite available treatments, approximately one-third of patients exhibit resistance to standar...
BACKGROUND: The demethylation is suspected to play a role in the development of major depressive disorder (MDD), but the precise biological mechanisms remain unclear. Therefore, this study aimed to investigate biomarkers linked to demethylation in MD...
BACKGROUND: Identifying key areas of brain dysfunction in mental illness is critical for developing precision diagnosis and treatment. This study aimed to develop region-specific brain aging trajectory prediction models using multimodal magnetic reso...
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