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Depressive Disorder, Major

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Intelligent classification of major depressive disorder using rs-fMRI of the posterior cingulate cortex.

Journal of affective disorders
Major Depressive Disorder (MDD) is a widespread psychiatric condition that affects a significant portion of the global population. The classification and diagnosis of MDD is crucial for effective treatment. Traditional methods, based on clinical asse...

Graph convolutional network with attention mechanism improve major depressive depression diagnosis based on plasma biomarkers and neuroimaging data.

Journal of affective disorders
BACKGROUND: The absence of clinically-validated biomarkers or objective protocols hinders effective major depressive disorder (MDD) diagnosis. Compared to healthy control (HC), MDD exhibits anomalies in plasma protein levels and neuroimaging presenta...

At-home, telehealth-supported ketamine treatment for depression: Findings from longitudinal, machine learning and symptom network analysis of real-world data.

Journal of affective disorders
BACKGROUND: Improving safe and effective access to ketamine therapy is of high priority given the growing burden of mental illness. Telehealth-supported administration of sublingual ketamine is being explored toward this goal.

Development and validation of a machine learning model for prediction of comorbid major depression disorder among narcolepsy type 1.

Sleep medicine
BACKGROUND: Major depression disorder (MDD) forms a common psychiatric comorbidity among patients with narcolepsy type 1 (NT1), yet its impact on patients with NT1 is often overlooked by neurologists. Currently, there is a lack of effective methods f...

MicroRNA classification and discovery for major depressive disorder diagnosis: Towards a robust and interpretable machine learning approach.

Journal of affective disorders
BACKGROUND: Major depressive disorder (MDD) is notably underdiagnosed and undertreated due to its complex nature and subjective diagnostic methods. Biomarker identification would help provide a clearer understanding of MDD aetiology. Although machine...

An integrated machine learning framework for developing and validating a diagnostic model of major depressive disorder based on interstitial cystitis-related genes.

Journal of affective disorders
BACKGROUND: Major depressive disorder (MDD) and interstitial cystitis (IC) are two highly debilitating conditions that often coexist with reciprocal effect, significantly exacerbating patients' suffering. However, the molecular underpinnings linking ...

Emergency department risk model: timely identification of patients for outpatient care coordination.

The American journal of managed care
OBJECTIVE: Major depressive disorder (MDD) is linked to a 61% increased risk of emergency department (ED) visits and frequent ED usage. Collaborative care management (CoCM) models target MDD treatment in primary care, but how best to prioritize patie...

GCTNet: a graph convolutional transformer network for major depressive disorder detection based on EEG signals.

Journal of neural engineering
Identifying major depressive disorder (MDD) using objective physiological signals has become a pressing challenge.Hence, this paper proposes a graph convolutional transformer network (GCTNet) for accurate and reliable MDD detection using electroencep...

Enhancing Major Depressive Disorder Diagnosis With Dynamic-Static Fusion Graph Neural Networks.

IEEE journal of biomedical and health informatics
Major Depressive Disorder (MDD) is a debilitating, complex mental condition with unclear mechanisms hindering diagnostic progress. Research links MDD to abnormal brain connectivity using functional magnetic resonance imaging (fMRI). Yet, existing fMR...