AIMC Topic: Drug Administration Schedule

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Prediction of Prolonged Opioid Use After Surgery in Adolescents: Insights From Machine Learning.

Anesthesia and analgesia Aug 1, 2021
BACKGROUND: Long-term opioid use has negative health care consequences. Patients who undergo surgery are at risk for prolonged opioid use after surgery (POUS). While risk factors have been previously identified, no methods currently exist to determin...
Child Treatment Outcome Age Factors Risk Assessment Adolescent Time Factors Pain Management Surgical Procedures, Operative Drug Administration Schedule Predictive Value of Tests Pain, Postoperative Analgesics, Opioid Decision Support Techniques Retrospective Studies Female Risk Factors Young Adult Male Humans Machine Learning
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Can Predictive Modeling Tools Identify Patients at High Risk of Prolonged Opioid Use After ACL Reconstruction?

Clinical orthopaedics and related research Jul 1, 2020
BACKGROUND: Machine-learning methods such as the Bayesian belief network, random forest, gradient boosting machine, and decision trees have been used to develop decision-support tools in other clinical settings. Opioid abuse is a problem among civili...
Adult Male Risk Assessment Reproducibility of Results Risk Factors Young Adult Opioid-Related Disorders Drug Administration Schedule Arthroscopy Time Factors Treatment Outcome Pain, Postoperative Machine Learning Decision Support Techniques Databases, Factual Retrospective Studies Clinical Decision-Making Female Humans Military Medicine Anterior Cruciate Ligament Injuries Anterior Cruciate Ligament Reconstruction Narcotic Antagonists
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Evaluation of the potential nephrotoxicity and mechanism in rats after long-term exposure to the traditional Tibetan medicine tsothel.

Pharmaceutical biology Dec 1, 2018
CONTEXT: Tsothel, a traditional Tibetan medicine, is regarded as 'the king of essences'. Nevertheless, tsothel has aroused serious concern regarding its biosafety because its main component is HgS. Unfortunately, toxicological studies on tsothel are ...
Drugs, Chinese Herbal Kidney Female Drug Evaluation, Preclinical Medicine, Tibetan Traditional Rats Drug Administration Schedule Rats, Sprague-Dawley Animals Mercury Compounds Male
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Spontaneous withdrawal in intermittent morphine administration in rats and mice: effect of clonidine coadministration and sex-related differences.

Turkish journal of medical sciences Jan 1, 2015
BACKGROUND/AIM: Treating animals repeatedly with intermittent and increasing morphine doses has been suggested to allow some withdrawal during each dosing interval, which causes repeated stress. The present study aimed to test this hypothesis and ass...
Substance Withdrawal Syndrome Mice, Inbred Strains Naloxone Narcotic Antagonists Mice, Inbred BALB C Dose-Response Relationship, Drug Analgesics Animals Male Rats, Wistar Drug Administration Schedule Clonidine Female Grooming Analgesics, Opioid Morphine Sex Factors
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Control of HIV/AIDS infection system with drug dosages design via robust H(∞) fuzzy controller.

Bio-medical materials and engineering Jan 1, 2015
The designing of H∞ fuzzy controller for HIV/AIDS infected dynamic system has been considered in this paper. With TS fuzzy model and LMIs approach, the proposed controller is obtained for such a system. A set of sufficient conditions of the H∞ contro...
Drug Administration Schedule Drug Therapy, Computer-Assisted Fuzzy Logic CD4 Lymphocyte Count CD4-Positive T-Lymphocytes Humans Feedback HIV Infections Anti-HIV Agents Treatment Outcome
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[Retreatment strategies for the patients with HCV infection].

Przeglad epidemiologiczny Jan 1, 2005
Despite recent advances in the treatment of chronic hepatitis C, especially introduction of combined therapy with pegylated interferons with ribavirin, significant number of patients fails to achieve sustained virologic response. Such patients may be...
Recombinant Proteins Treatment Outcome Randomized Controlled Trials as Topic Interferon-alpha Polyethylene Glycols Interferon alpha-2 Humans Antiviral Agents Retreatment Drug Administration Schedule Ribavirin Recurrence Quality-Adjusted Life Years Drug Therapy, Combination Hepatitis C, Chronic
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