AIMC Topic: Drug Delivery Systems

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Comparative examination of the chemistry and biology of AI-driven gold NPs in Theranostics: New insights into biosensing, bioimaging, genomics, diagnostics, and therapy.

Nanomedicine : nanotechnology, biology, and medicine
Integrating artificial intelligence (AI) with nanomedicine is transforming Theranostics, driving advances in biosensing, bioimaging, genomics, diagnostics, and treatment. This review highlights the latest advancements in AI-driven nanomedicine, focus...

Recent advances in cutaneous drug delivery by iontophoresis.

Expert opinion on drug delivery
INTRODUCTION: Iontophoresis has been extensively studied for topical and transdermal drug delivery to stimulate the absorption of molecules that would hardly pass through the outermost layer of the skin passively. Recent research has focused on its c...

An integrated microfluidic and fluorescence platform for probing in vivo neuropharmacology.

Neuron
Neurotechnologies and genetic tools for dissecting neural circuit functions have advanced rapidly over the past decade although the development of complementary pharmacological methodologies has comparatively lagged. Understanding the precise pharmac...

Smart MXene-based microrobots for targeted drug delivery and synergistic therapies.

Nanoscale
MXenes and their composites exhibit remarkable electrical conductivity, mechanical flexibility, and biocompatibility, making them ideal candidates for microrobot fabrication. Their tunable surface chemistry allows for easy functionalization, which en...

Smart nanomedicines powered by artificial intelligence: a breakthrough in lung cancer diagnosis and treatment.

Medical oncology (Northwood, London, England)
Lung cancer remains one of the leading causes of cancer-related mortality worldwide, primarily due to challenges in early detection, suboptimal therapeutic efficacy, and severe adverse effects associated with conventional treatments. The convergence ...

Multiple Instance Learning-Based Prediction of Blood-Brain Barrier Opening Outcomes Induced by Focused Ultrasound.

IEEE transactions on bio-medical engineering
OBJECTIVE: Targeted blood-brain barrier (BBB) opening using focused ultrasound (FUS) and micro/nanobubbles is a promising method for brain drug delivery. This study aims to explore the feasibility of multiple instance learning (MIL) in accurate and f...

Utilization of machine learning approach for production of optimized PLGA nanoparticles for drug delivery applications.

Scientific reports
This study investigates utilization of machine learning for the regression task of predicting the size of PLGA (Poly lactic-co-glycolic acid) nanoparticles. Various inputs including category and numeric were considered for building the model to predi...

AI-driven innovations in smart multifunctional nanocarriers for drug and gene delivery: A mini-review.

Critical reviews in oncology/hematology
The convergence of artificial intelligence (AI) and nanomedicine has revolutionized the design of smart multifunctional nanocarriers (SMNs) for drug and gene delivery, offering unprecedented precision, efficiency, and personalization in therapeutic a...

Living material-derived intelligent micro/nanorobots.

Biomaterials science
Living materials, which include various types of cells, organelles, and biological components from animals, plants, and microorganisms, have become central to recent investigations in micro and nanorobotics. Living material-derived intelligent micro/...

Machine learning-assisted design of immunomodulatory lipid nanoparticles for delivery of mRNA to repolarize hyperactivated microglia.

Drug delivery
Regulating inflammatory microglia presents a promising strategy for treating neurodegenerative and autoimmune disorders, yet effective therapeutic agents delivery to these cells remains a challenge. This study investigates modified lipid nanoparticle...