Studies in health technology and informatics
May 15, 2025
Multimorbidity is increasingly prevalent as the population ages and individuals with multiple long-term conditions (MLTCs) live longer. Often each condition is treated by a separate clinician, which can lead to harmful drug-drug and drug-disease inte...
BACKGROUND: Research on chronic multimorbidity has increasingly become a focal point with the aging of the population. Many studies in this area require detailed patient characteristic information. However, the current methods for extracting such inf...
BACKGROUND: Progression-free survival (PFS) is a crucial endpoint in cancer drug research. Clinician-confirmed cancer progression, namely real-world PFS (rwPFS) in unstructured text (ie, clinical notes), serves as a reasonable surrogate for real-worl...
BACKGROUND: Information overload in electronic health records requires effective solutions to alleviate clinicians' administrative tasks. Automatically summarizing clinical text has gained significant attention with the rise of large language models....
BACKGROUND: The integration of diverse clinical data sources requires standardization through models such as Observational Medical Outcomes Partnership (OMOP). However, mapping data elements to OMOP concepts demands significant technical expertise an...
BACKGROUND: Symptoms are a core concept of nursing interest. Large-scale secondary data reuse of notes in electronic health records (EHRs) has the potential to increase the quantity and quality of symptom research. However, the symptom language used ...
Managing chronic diseases requires ongoing monitoring of disease activity and therapeutic responses to optimize treatment plans. With the growing availability of disease-modifying therapies, it is crucial to investigate comparative effectiveness and ...
Predicting treatment response is an important problem in real-world applications, where the heterogeneity of the treatment response remains a significant challenge in practice. Unsupervised machine learning methods have been proposed to address this ...
BACKGROUND: Synthetic electronic health records (EHRs) generated by large language models (LLMs) offer potential for clinical education and model training while addressing privacy concerns. However, performance variations and demographic biases in th...
In a recent study, the effectiveness of GPT-4 Omni in transforming lobectomy surgical records into structured data across multiple languages was explored. The aim was to improve both efficiency and accuracy in documenting thoracic surgical oncology p...
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