AIMC Topic: Encephalomyelitis, Autoimmune, Experimental

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Machine learning and multi-omics integration identifies immunological predictors and mechanistic insights in autoimmune encephalitis.

Inflammation research : official journal of the European Histamine Research Society ... [et al.] Jan 14, 2026
OBJECTIVE: To develop an interpretable prognostic prediction model for autoimmune encephalitis (AE) using immunological indicators and to investigate the potential role of nucleophosmin (NPM1) in disease pathogenesis through multi-omics approaches.
Humans Machine Learning Prognosis Female Adult Animals Male Middle Aged Transcriptome Multiomics Nuclear Proteins Autoantibodies Hashimoto Disease Nucleophosmin Encephalitis Encephalomyelitis, Autoimmune, Experimental
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3-Dimensional Immunostaining and Automated Deep-Learning Based Analysis of Nerve Degeneration.

International journal of molecular sciences Nov 26, 2022
Multiple sclerosis (MS) is an autoimmune and neurodegenerative disease driven by inflammation and demyelination in the brain, spinal cord, and optic nerve. Optic neuritis, characterized by inflammation and demyelination of the optic nerve, is a sympt...
Animals Deep Learning Mice Inflammation Disease Models, Animal Mice, Inbred C57BL Neurodegenerative Diseases Multiple Sclerosis Optic Neuritis Nerve Degeneration Encephalomyelitis, Autoimmune, Experimental
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