BACKGROUND: Objective measures using accelerometer-based activity monitors have been extensively used in physical activity (PA) and sedentary behavior (SB) research. To measure PA and SB precisely, the field is shifting towards machine learning-based...
Previous ankle exoskeleton assistance techniques that were able to demonstrate metabolic reductions can be categorized into those that delivered moment profiles similar to the biological ankle moment throughout the stance phase, and others that deliv...
Proceedings of the National Academy of Sciences of the United States of America
Jan 2, 2019
Biophysical interactions between proteins and peptides are key determinants of molecular recognition specificity landscapes. However, an understanding of how molecular structure and residue-level energetics at protein-peptide interfaces shape these l...
BMC medical informatics and decision making
Dec 12, 2018
BACKGROUND: There has been an increasing interest in understanding the usefulness of wrist-based accelerometer data for physical activity (PA) assessment due to the ease of use and higher user compliance than other body placements. PA assessment stud...
Clinical nutrition (Edinburgh, Scotland)
Oct 1, 2018
BACKGROUND & AIMS: The resting energy expenditure (REE) determination is important in nutrition for adequate dietary prescription. The gold standard i.e. indirect calorimetry is not available in clinical settings. Thus, several predictive equations h...
BACKGROUND: Stair ascent is one of the most important and challenging activities of daily living to maintain mobility and independence in elderly adults. Recently, various types of wearable walking assist robots have been developed to improve gait fu...
IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Sep 1, 2018
Lower-limb amputees typically experience reduced mobility and higher metabolic rates than non-amputees. It may be possible to improve their mobility and metabolic rate with an optimized robotic prosthesis. Here, we use large-scale trajectory optimiza...
Journal of neuroengineering and rehabilitation
Aug 9, 2018
BACKGROUND: Many gait impairments are characterized by asymmetry and result in reduced mobility. Exoskeletons could be useful for restoring gait symmetry by assisting only one leg. However, we still have limited understanding of the effects of unilat...
The Journal of neuroscience : the official journal of the Society for Neuroscience
Aug 8, 2018
Persistent spiking has been thought to underlie working memory (WM). However, virtually all of the evidence for this comes from studies that averaged spiking across time and across trials, which masks the details. On single trials, activity often occ...
Journal of neuroengineering and rehabilitation
Jul 13, 2018
BACKGROUND: Soft exosuits are a recent approach for assisting human locomotion, which apply assistive torques to the wearer through functional apparel. Over the past few years, there has been growing recognition of the importance of control individua...