Improving accuracy and timeliness for osteoporosis diagnosis could help prevent fragility fractures, morbidity, and mortality for older individuals. Osteoporosis is an often silent health condition, especially as regards vertebral fractures, and WHO ...
Infertility affects millions of couples worldwide, and in vitro fertilization is a key therapeutic strategy for achieving parenthood. Despite advances, the first IVF attempt fails in ~60% of patients, highlighting the need for innovative solutions to...
BACKGROUND: Liver fibrosis is a pathological outcome of chronic liver injury and a hallmark of multiple chronic liver diseases. Magnetic resonance elastography (MRE) provides a non-invasive modality for evaluating the severity of liver fibrosis.
BACKGROUND: Coronary heart disease (CHD) continues to be a leading cause of global morbidity and mortality, with patients undergoing percutaneous coronary intervention (PCI) facing a significant risk of recurrent cardiovascular events. While secondar...
Epidemiology and psychiatric sciences
Oct 20, 2025
AIMS: The epidemiology and age-specific patterns of lifetime suicide attempts (LSA) in China remain unclear. We aimed to examine age-specific prevalence and predictors of LSA among Chinese adults using machine learning (ML).
Vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have demonstrated strong efficacy in preventing symptomatic disease, but adverse cardiovascular side effects have been reported. This study investigated whether noninvasive...
Proceedings of the National Academy of Sciences of the United States of America
Oct 17, 2025
Speech comprehension involves transforming an acoustic waveform into meaning. To do so, the human brain generates a hierarchy of features that converts the sensory input into increasingly abstract language properties. However, little is known about h...
BACKGROUND: Rheumatoid arthritis (RA), particularly seronegative disease, is difficult to diagnose early, which can delay treatment initiation. This study aims to develop a binary DNA methylation (DNAm)-based algorithm to diagnose RA.
BACKGROUND: The advancement of digital technologies has brought transformative changes across the healthcare sector, and nursing is no exception. However, existing research has largely overlooked the ethical challenges nursing students face in real-w...
BACKGROUND: It remains unclear whether certain individuals with type 2 diabetes (T2D) derive greater cardiovascular benefit from GLP-1 receptor agonists (GLP-1RAs). Here, we integrate individual-level data from cardiovascular outcome trials (CVOTs) a...
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