Cervical cancer, predominantly caused by Human Papillomavirus (HPV) infection, remains a significant global health burden for women, contributing to elevated morbidity and mortality rates. Early and accurate prediction is critical in improving patien...
About 30% of temporal lobe epilepsy (TLE) cases are negative on MRI, so quantitative diagnosis based on clinical symptoms becomes challenging. There is an urgent need for an accurate and reliable method to differentiate patients with MRI-negative TLE...
Therapeutic options for refractory depression are urgently needed. We conducted a deep brain stimulation (DBS) randomized controlled trial of the bed nucleus of the stria terminalis (BNST), an extended amygdala structure, and nucleus accumbens (NAc) ...
Accurate prognostication is essential to guide clinical management in localised cutaneous melanoma (CM), the form of skin cancer with the highest mortality. While the tumour microenvironment (TME) plays a key role in disease progression, current stag...
INTRODUCTION: High-flow nasal cannula (HFNC) is an important treatment option for acute hypoxic respiratory failure and can improve outcomes. However, patients on a prolonged duration of HFNC have worse clinical outcomes and increased mortality. It i...
BACKGROUND: Emergency departments (EDs) routinely screen for fall risk, but patients are rarely notified of their results or referred to preventive resources. There is a critical need for an intervention that notifies patients when they are at risk f...
International journal of colorectal disease
Nov 18, 2025
PURPOSE: Early colorectal cancer (CRC) detection is crucial for effective treatment; however, traditional screening methods face challenges. Colonoscopy, though highly effective, has limited availability, and fecal immunochemical tests (FIT) are more...
Cancer immunology, immunotherapy : CII
Nov 18, 2025
Immunohistochemistry (IHC) remains the gold standard for evaluating protein expression in tumor microenvironment analysis. This approach hinders robust correlation analyses between spatial heterogeneity in the tumor microenvironment and clinical outc...
This study examines the function of chromatin-remodeling genes (CRGs) in nasopharyngeal carcinoma (NPC), with an emphasis on their potential as prognostic and diagnostic biomarkers. We examined gene expression information collected from multiple data...
Deep Learning methods have become a powerful tool in medical imaging, with great potential to improve diagnostic accuracy and support early disease detection. This is especially critical for breast cancer, one of the most common cancers among women, ...
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