AIMC Topic: Genotype

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Predicting laboratory aspirin resistance in Chinese stroke patients using machine learning models by GP1BA polymorphism.

Pharmacogenomics Oct 23, 2024
This study aims to use machine learning model to predict laboratory aspirin resistance (AR) in Chinese stroke patients by incorporating patient characteristics and single nucleotide polymorphisms of and . 2405 patients were analyzed to measure the M...
China Platelet Aggregation Inhibitors Aged Polymorphism, Single Nucleotide Drug Resistance Male Genotype East Asian People Humans Middle Aged Machine Learning Stroke Female Aspirin
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Genotype-specific responses to drought stress in myrtle ( L.): integrating machine learning techniques.

PeerJ Oct 7, 2024
BACKGROUND: Myrtle ( L.), native to the Mediterranean region of Türkiye, is a valuable plant with applications in traditional medicine, pharmaceuticals, and culinary practices. Understanding how myrtle responds to water stress is essential for sustai...
Genotype Stress, Physiological Myrtus Droughts Machine Learning
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ProTformer: Transformer-based model for superior prediction of protein content in lablab bean (Lablab purpureus L.) using Near-Infrared Reflectance spectroscopy.

Food research international (Ottawa, Ont.) Oct 1, 2024
Lablab bean (Lablab purpureus L.), known for its higher protein content provides a promising alternative to reduce reliance on animal-based proteins and support sustainable agriculture. Nowadays, traditional methods for nutritional profiling have bee...
Least-Squares Analysis Fabaceae Nutritive Value Plant Proteins Neural Networks, Computer Spectroscopy, Near-Infrared Genotype
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Enhancing Gene Expression Predictions Using Deep Learning and Functional Annotations.

Genetic epidemiology Sep 30, 2024
Transcriptome-wide association studies (TWAS) aim to uncover genotype-phenotype relationships through a two-stage procedure: predicting gene expression from genotypes using an expression quantitative trait locus (eQTL) data set, then testing the pred...
Models, Genetic Gene Expression Quantitative Trait Loci Genome-Wide Association Study Polymorphism, Single Nucleotide Genotype Phenotype Transcriptome Deep Learning Humans
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Ensemble and optimization algorithm in support vector machines for classification of wheat genotypes.

Scientific reports Sep 30, 2024
This study aimed to classifying wheat genotypes using support vector machines (SVMs) improved with ensemble algorithms and optimization techniques. Utilizing data from 302 wheat genotypes and 14 morphological attributes to evaluate six SVM kernels: l...
Support Vector Machine Algorithms Triticum Genotype
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A deep learning approach to prediction of blood group antigens from genomic data.

Transfusion Sep 13, 2024
BACKGROUND: Deep learning methods are revolutionizing natural science. In this study, we aim to apply such techniques to develop blood type prediction models based on cheap to analyze and easily scalable screening array genotyping platforms.
Humans Neural Networks, Computer Female Finland Genotype Male Denmark Blood Group Antigens Deep Learning Blood Donors Genomics
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Semi-supervised machine learning method for predicting homogeneous ancestry groups to assess Hardy-Weinberg equilibrium in diverse whole-genome sequencing studies.

American journal of human genetics Sep 12, 2024
Large-scale, multi-ethnic whole-genome sequencing (WGS) studies, such as the National Human Genome Research Institute Genome Sequencing Program's Centers for Common Disease Genomics (CCDG), play an important role in increasing diversity for genetic r...
Humans Genetics, Population Genotype Genome-Wide Association Study Whole Genome Sequencing Supervised Machine Learning Polymorphism, Single Nucleotide Ethnicity Genome, Human
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Machine Learning and Imputation to Characterize Human Norovirus Genotype Susceptibility to Sodium Hypochlorite.

Food and environmental virology Sep 11, 2024
Human norovirus (HuNoV) is the leading cause of foodborne illness in the developed world and a major contributor to gastroenteritis globally. Its low infectious dose and environmental persistence necessitate effective disinfection protocols. Sodium h...
Machine Learning Genotype Disinfection Humans Caliciviridae Infections Norovirus Sodium Hypochlorite Disinfectants Gastroenteritis
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Development and validation of machine-learning models of diet management for hyperphenylalaninemia: a multicenter retrospective study.

BMC medicine Sep 11, 2024
BACKGROUND: Assessing dietary phenylalanine (Phe) tolerance is crucial for managing hyperphenylalaninemia (HPA) in children. However, traditionally, adjusting the diet requires significant time from clinicians and parents. This study aims to investig...
Phenylalanine Phenylketonurias Phenylalanine Hydroxylase Child, Preschool Child Genotype Machine Learning Retrospective Studies Female Male Infant Adolescent Humans
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Application of Machine Learning Algorithms for Risk Stratification and Efficacy Evaluation in Cervical Cancer Screening among the ASCUS/LSIL Population: Evidence from the Korean HPV Cohort Study.

Cancer research and treatment Sep 6, 2024
PURPOSE: We assessed human papillomavirus (HPV) genotype-based risk stratification and the efficacy of cytology testing for cervical cancer screening in patients with atypical squamous cells of undetermined significance (ASCUS)/low-grade squamous int...
Genotype Papillomavirus Infections Early Detection of Cancer Middle Aged Risk Assessment Cohort Studies Papillomaviridae Atypical Squamous Cells of the Cervix Algorithms Republic of Korea Female Aged Adult Uterine Cervical Neoplasms Humans Machine Learning
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