AIMC Topic: Glomerulonephritis, IGA

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Machine learning-based diagnostic prediction of IgA nephropathy: model development and validation study.

Scientific reports
IgA nephropathy progresses to kidney failure, making early detection important. However, definitive diagnosis depends on invasive kidney biopsy. This study aimed to develop non-invasive prediction models for IgA nephropathy using machine learning. We...

Development and External Validation of a Multidimensional Deep Learning Model to Dynamically Predict Kidney Outcomes in IgA Nephropathy.

Clinical journal of the American Society of Nephrology : CJASN
KEY POINTS: A dynamic model predicts IgA nephropathy prognosis based on deep learning. Longitudinal clinical data and deep learning improve predictive accuracy and interpretability in GN.

Development of a novel combined nomogram model integrating deep learning radiomics to diagnose IgA nephropathy clinically.

Renal failure
This study aimed to develop and validate a combined nomogram model based on superb microvascular imaging (SMI)-based deep learning (DL), radiomics characteristics, and clinical factors for noninvasive differentiation between immunoglobulin A nephropa...

Performance and limitations of a supervised deep learning approach for the histopathological Oxford Classification of glomeruli with IgA nephropathy.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: The Oxford Classification for IgA nephropathy is the most successful example of an evidence-based nephropathology classification system. The aim of our study was to replicate the glomerular components of Oxford scoring with ...

Automated Prediction of Kidney Failure in IgA Nephropathy with Deep Learning from Biopsy Images.

Clinical journal of the American Society of Nephrology : CJASN
BACKGROUND AND OBJECTIVES: Digital pathology and artificial intelligence offer new opportunities for automatic histologic scoring. We applied a deep learning approach to IgA nephropathy biopsy images to develop an automatic histologic prognostic scor...

An Interpretable Machine Learning Survival Model for Predicting Long-term Kidney Outcomes in IgA Nephropathy.

AMIA ... Annual Symposium proceedings. AMIA Symposium
IgA nephropathy (IgAN) is common worldwide and has heterogeneous phenotypes. Predicting long-term outcomes is important for clinical decision-making. As right-censored patients become common during the long-term follow-up, either excluding these pati...

Identification of glomerular lesions and intrinsic glomerular cell types in kidney diseases via deep learning.

The Journal of pathology
Identification of glomerular lesions and structures is a key point for pathological diagnosis, treatment instructions, and prognosis evaluation in kidney diseases. These time-consuming tasks require a more accurate and reproducible quantitative analy...

Screening and Bioinformatics Analysis of IgA Nephropathy Gene Based on GEO Databases.

BioMed research international
PURPOSE: To identify novel biomarkers of IgA nephropathy (IgAN) through bioinformatics analysis and elucidate the possible molecular mechanism.

IgA nephropathy in systemic lupus erythematosus patients: case report and literature review.

Revista brasileira de reumatologia
Systemic erythematosus lupus (SLE) is a multisystemic autoimmune disease which has nephritis as one of the most striking manifestations. Although it can coexist with other autoimmune diseases, and determine the predisposition to various infectious co...