AIMC Topic: Glycated Hemoglobin

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The Role of HbA1c in Parkinson's Disease: An Integrative Analysis by Single-Cell, Bulk Transcriptome and Mendelian Randomization.

Molecular neurobiology
Decreased glucose tolerance is recognized as a factor associated with Parkinson's disease (PD) progression, yet the relationship between HbA1c and PD prognosis remains insufficiently explored. Using data from the Integrated Epidemiological Unit (IEU)...

Effectiveness of AI-driven interventions in glycemic control: A systematic review and meta-analysis of randomized controlled trials.

Primary care diabetes
This systematic review aims to assess the effectiveness of AI-Driven Decision Support Systems in improving glycemic control, measured by Time in Range (TIR) and HbA1c levels, in patients with diabetes. Included studies were randomized controlled tria...

Predictive factors of hypoglycemia in type 2 diabetes: a prospective study using machine learning.

Scientific reports
Hypoglycemia is a serious complication in individuals with type 2 diabetes mellitus. Identifying who is most at risk remains challenging due to the non-linear relationships between hypoglycemia and its associated risk factors. The objective of this s...

Development of a 5-Year Risk Prediction Model for Transition From Prediabetes to Diabetes Using Machine Learning: Retrospective Cohort Study.

Journal of medical Internet research
BACKGROUND: Diabetes has emerged as a critical global public health crisis. Prediabetes, as the transitional phase with 5%-10% annual progression to diabetes, offers a critical window for intervention. The lack of a 5-year risk prediction model for d...

Real-Time AI-Assisted Insulin Titration System for Glucose Control in Patients With Type 2 Diabetes: A Randomized Clinical Trial.

JAMA network open
IMPORTANCE: Type 2 diabetes (T2D) is one of the most prevalent chronic diseases in the world. Insulin titration for glycemic control in T2D is crucial but limited by the lack of personalized and real-time tools.

Non-Linear Dose-Response Relationship for Metformin in Japanese Patients With Type 2 Diabetes: Analysis of Irregular Longitudinal Data by Interpretable Machine Learning Models.

Pharmacology research & perspectives
The dose-response relationship between metformin and change in hemoglobin A1c (HbA1c) shows a maximum at 1500-2000 mg/day in patients with type 2 diabetes (T2D) in the U.S. In Japan, there is little evidence on the HbA1c-lowering effect of high-dose ...

Development and Validation of Machine Learning Models for Identifying Prediabetes and Diabetes in Normoglycemia.

Diabetes/metabolism research and reviews
BACKGROUND: Prediabetes and diabetes are both abnormal states of glucose metabolism (AGM) that can lead to severe complications. Early detection of AGM is crucial for timely intervention and treatment. However, fasting blood glucose (FBG) as a mass p...

Prediction of Poor Glycemic Control in Children with Type 1 Diabetes.

Studies in health technology and informatics
This study developed and validated a machine learning model for predicting glycemic control in children with type 1 diabetes at the time of diagnosis, revealing age at diagnosis as the most informative predictor.

Association between serum Galectin-3 and periodontitis in patients with type 2 diabetes mellitus.

Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology
OBJECTIVES: This study aims to investigate the correlation between serum Galectin-3 levels and the risk of periodontitis in patients with type 2 diabetes mellitus (T2DM).